<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-20T12:08:34Z</responseDate><request verb="GetRecord" identifier="oai:dspace.mit.edu:1721.1/42154" metadataPrefix="dim">https://dspace.mit.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:dspace.mit.edu:1721.1/42154</identifier><datestamp>2022-01-13T07:54:33Z</datestamp><setSpec>com_1721.1_7582</setSpec><setSpec>com_1721.1_7581</setSpec><setSpec>col_1721.1_131023</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="advisor" lang="en_US">Mark Keegan and Darrell J. Irvine.</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">King, Connie Hong-Yee</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="other" lang="en_US">Massachusetts Institute of Technology. Dept. of Materials Science and Engineering.</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="department">Massachusetts Institute of Technology. Department of Materials Science and Engineering</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2008-09-03T14:44:38Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="available">2008-09-03T14:44:38Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="issued" lang="en_US">2007</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="uri">http://hdl.handle.net/1721.1/42154</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="oclc" lang="en_US">228504392</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007.</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">"September 2007."</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Includes bibliographical references (p. 67-72).</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">As the number of individuals suffering from tissue loss and end-stage organ failure continues to grow, researchers are turning to tissue engineering to provide better methods of treatment. The field, however, still faces many technical challenges that are limiting its applications. One challenge faced in engineering more complex tissues and organs is the need for inherent microvasculature to supply the tissue with nutrients and oxygen. Researchers at The Charles Stark Draper Laboratory have developed a method for engineering microvascular networks in vitro using various microfabrication techniques. This paper discusses the current state of the research and technical challenges to overcome before commercializing the technology. The feasibility of using the networks in the nearer term application of treating chronic wounds will also be assessed, and a potential business strategy will be laid out.</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="statementofresponsibility" lang="en_US">by Connie Hong-Yee King.</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="degree" lang="en_US">M.Eng.</dim:field>
   <dim:field mdschema="dc" element="format" qualifier="extent" lang="en_US">72 p.</dim:field>
   <dim:field mdschema="dc" element="language" qualifier="iso" lang="en_US">eng</dim:field>
   <dim:field mdschema="dc" element="publisher" lang="en_US">Massachusetts Institute of Technology</dim:field>
   <dim:field mdschema="dc" element="rights" lang="en_US">M.I.T. theses are protected by 
copyright. They may be viewed from this source for any purpose, but 
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permission. See provided URL for inquiries about permission.</dim:field>
   <dim:field mdschema="dc" element="rights" qualifier="uri" lang="en_US">http://dspace.mit.edu/handle/1721.1/7582</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Materials Science and Engineering.</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">Assessment of in vitro engineered microvascular networks and their application in the treatment of chronic wounds</dim:field>
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   	&lt;Title>Assessment of in vitro engineered microvascular networks and their application in the treatment of chronic wounds&lt;/Title>
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   	&lt;PublicationDate>2007&lt;/PublicationDate>
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    &lt;Keyword>Materials Science and Engineering.&lt;/Keyword>
   	&lt;Abstract>As the number of individuals suffering from tissue loss and end-stage organ failure continues to grow, researchers are turning to tissue engineering to provide better methods of treatment. The field, however, still faces many technical challenges that are limiting its applications. One challenge faced in engineering more complex tissues and organs is the need for inherent microvasculature to supply the tissue with nutrients and oxygen. Researchers at The Charles Stark Draper Laboratory have developed a method for engineering microvascular networks in vitro using various microfabrication techniques. This paper discusses the current state of the research and technical challenges to overcome before commercializing the technology. The feasibility of using the networks in the nearer term application of treating chronic wounds will also be assessed, and a potential business strategy will be laid out.&lt;/Abstract>
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