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Guoan Li and Derek Rowell. Suggs, Jeremy F. (Jeremy Floyd), 1976- Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Department of Mechanical Engineering 2008-09-03T15:15:52Z 2008-09-03T15:15:52Z 2007 2007 http://hdl.handle.net/1721.1/42297 232358861 Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. Includes bibliographical references (p. 240-271). While contempary total knee arthroplasty has been successful in improving the quality of life for those suffering from severe osteoarthritis, the function of these patients has not reached normal levels for their age group. Thus, there is an increasing need to improve total knee arthroplasty techniques to allow patients to function normally. We currently have limited knowledge about how current knee arthroplasties behave in-vivo, but this information could be pivotal in designing new implants and surgical techniques. Therefore, the objective of this work was to develop the Dual Fluoroscopic Imaging System, a non-invasive imaging system capable of measuring in-vivo knee kinematics in all degrees of freedom. This system was used to investigate factors that may affect patient function after total knee arthroplasty. The feasibility of using kinematic data obtained using this system to analyze wear of the polyethylene insert was also explored The system was shown to be repeatable and accurate in determining the pose of the TKA components in all degrees of freedom. Six degree-of-freedom kinematics and articular contact motion were measured in-vivo. Data was obtained for patients with two typical classes of TKA, cruciate-retaining and cruciate-substituting, and the function of conventional implants was compared to that of more recent high flexion designs. In general, no differences were detected between these groups. Further, no factors such as age, weight, PCL management, or kinematics, were found to correlate with flexion capability. Future studies should investigate changes in knee structures from the preoperative state to the postoperative state. Preliminary estimates of polyethylene stresses suggested great potential in using the Dual Fluoroscopic Imaging System in developing a model of in-vivo polyethylene wear. by Jeremy F. Suggs. Sc.D. 271 p. eng Massachusetts Institute of Technology M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 Mechanical Engineering. Investigation of in-vivo total knee arthroplasty biomechanics using a dual fluoroscopic imaging system Thesis application/pdf false Publication unknown unknown <Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="d77ee49a-3041-4f35-bf66-d00f5b463486"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Investigation of in-vivo total knee arthroplasty biomechanics using a dual fluoroscopic imaging system</Title> <PublishedIn> <Publication> </Publication> </PublishedIn> <PublicationDate>2007</PublicationDate> <Authors> <Author> <DisplayName>Suggs, Jeremy F. (Jeremy Floyd), 1976-</DisplayName> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Massachusetts Institute of Technology</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>http://dspace.mit.edu/handle/1721.1/7582</License> <Keyword>Mechanical Engineering.</Keyword> <Abstract>While contempary total knee arthroplasty has been successful in improving the quality of life for those suffering from severe osteoarthritis, the function of these patients has not reached normal levels for their age group. Thus, there is an increasing need to improve total knee arthroplasty techniques to allow patients to function normally. We currently have limited knowledge about how current knee arthroplasties behave in-vivo, but this information could be pivotal in designing new implants and surgical techniques. Therefore, the objective of this work was to develop the Dual Fluoroscopic Imaging System, a non-invasive imaging system capable of measuring in-vivo knee kinematics in all degrees of freedom. This system was used to investigate factors that may affect patient function after total knee arthroplasty. The feasibility of using kinematic data obtained using this system to analyze wear of the polyethylene insert was also explored The system was shown to be repeatable and accurate in determining the pose of the TKA components in all degrees of freedom. Six degree-of-freedom kinematics and articular contact motion were measured in-vivo. Data was obtained for patients with two typical classes of TKA, cruciate-retaining and cruciate-substituting, and the function of conventional implants was compared to that of more recent high flexion designs. In general, no differences were detected between these groups. Further, no factors such as age, weight, PCL management, or kinematics, were found to correlate with flexion capability. Future studies should investigate changes in knee structures from the preoperative state to the postoperative state. Preliminary estimates of polyethylene stresses suggested great potential in using the Dual Fluoroscopic Imaging System in developing a model of in-vivo polyethylene wear.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication>