2026-09-18T19:31:25Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/448682022-01-13T07:54:36Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Emilio Bizzi and Ian W. Hunter.
Bae, Woong Jin
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2009-03-16T19:53:37Z
2009-03-16T19:53:37Z
2008
2008
http://hdl.handle.net/1721.1/44868
302268472
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2008.
Includes bibliographical references (leaves 39-41).
The ability to record from the same neuron for extended periods of time is essential to understanding how the brain reorganizes during motor learning. Conventional chronic recording microelectrodes are made from metal or silicon. However, the large stiffness mismatch between the electrodes and brain tissue causes shear-induced inflammation, limiting long-term recording stability. The flexibility of a polypyrrole microwire has the potential to improve the chronic recording stability by minimizing the stiffness mismatch. This thesis shows the fabrication of conducting polymer electrodes and the stability of their impedance in physiological saline. The initial impedance was as low as 70 k[omega], but the electrode impedance increased by a factor of 10 when immersed in saline over 370 hours. This conducting polymer microwire electrode was implanted in a rodent brain and successfully used to record neuronal action potentials.
by Woong Jin Bae.
S.M.
41leaves
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Mechanical Engineering.
Cortical recording with conducting polymer electrodes
Thesis
application/pdf
false
Publication
unknown
unknown
<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="da38f6c6-9208-4c4e-9866-504fe6816297">
<Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type>
<Language>eng</Language>
<Title>Cortical recording with conducting polymer electrodes</Title>
<PublishedIn>
<Publication>
</Publication>
</PublishedIn>
<PublicationDate>2008</PublicationDate>
<Authors>
<Author>
<DisplayName>Bae, Woong Jin</DisplayName>
<Affiliation>
<OrgUnit>
</OrgUnit>
</Affiliation>
</Author>
</Authors>
<Editors>
</Editors>
<Publishers>
<Publisher>
<DisplayName>Massachusetts Institute of Technology</DisplayName>
<OrgUnit />
</Publisher>
</Publishers>
<License>http://dspace.mit.edu/handle/1721.1/7582</License>
<Keyword>Mechanical Engineering.</Keyword>
<Abstract>The ability to record from the same neuron for extended periods of time is essential to understanding how the brain reorganizes during motor learning. Conventional chronic recording microelectrodes are made from metal or silicon. However, the large stiffness mismatch between the electrodes and brain tissue causes shear-induced inflammation, limiting long-term recording stability. The flexibility of a polypyrrole microwire has the potential to improve the chronic recording stability by minimizing the stiffness mismatch. This thesis shows the fabrication of conducting polymer electrodes and the stability of their impedance in physiological saline. The initial impedance was as low as 70 k[omega], but the electrode impedance increased by a factor of 10 when immersed in saline over 370 hours. This conducting polymer microwire electrode was implanted in a rodent brain and successfully used to record neuronal action potentials.</Abstract>
<Access xmlns="http://purl.org/coar/access_right"
>
</Access>
</Publication>