2026-09-19T20:13:26Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/458102022-01-13T07:54:29Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Ali Khademhosseini and Utkan Demirci.
Brigham, Mark D
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
2009-06-30T16:20:54Z
2009-06-30T16:20:54Z
2007
2007
http://hdl.handle.net/1721.1/45810
319172522
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2007.
Includes bibliographical references (leaves 68-70).
Interpenetrating Polymer Networks (IPNs) represent a strategy for combining the properties of several polymeric materials into a single network. In this thesis, collagen and methacrylated hyaluronic acid are combined in IPNs to produce a range of new biocompatible. The fabrication method allows for control of compressive strength of the IPN hydrogels. The materials are confirmed to be homogeneous at microscopic scales with fluorescent techniques. The IPNs are used for cell encapsulation and have the potential to be used for surface cell culture. The mechanical properties can be adjusted to match those of cardiac tissue. Thus, when combined with the properties of biocompatibility, viable cell encapsulation, and cell culture, the collagenMeHA IPN hydrogels represent a powerful new material for tissue engineering applications.
by Mark D. Brigham.
M.Eng.
70 leaves
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Electrical Engineering and Computer Science.
Collagen and hyaluronic acid interpenetrating polymer networks for tissue engineering
Collagen and hyaluronic acid IPNs for tissue engineering
Thesis
application/pdf
Publication
unknown
unknown
<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="e789267d-0968-43dd-9fa1-7dde2fbffc06">
<Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type>
<Language>eng</Language>
<Title>Collagen and hyaluronic acid interpenetrating polymer networks for tissue engineering</Title>
<Subtitle>Collagen and hyaluronic acid IPNs for tissue engineering</Subtitle>
<PublishedIn>
<Publication>
</Publication>
</PublishedIn>
<PublicationDate>2007</PublicationDate>
<Authors>
<Author>
<DisplayName>Brigham, Mark D</DisplayName>
<Affiliation>
<OrgUnit>
</OrgUnit>
</Affiliation>
</Author>
</Authors>
<Editors>
</Editors>
<Publishers>
<Publisher>
<DisplayName>Massachusetts Institute of Technology</DisplayName>
<OrgUnit />
</Publisher>
</Publishers>
<License>http://dspace.mit.edu/handle/1721.1/7582</License>
<Keyword>Electrical Engineering and Computer Science.</Keyword>
<Abstract>Interpenetrating Polymer Networks (IPNs) represent a strategy for combining the properties of several polymeric materials into a single network. In this thesis, collagen and methacrylated hyaluronic acid are combined in IPNs to produce a range of new biocompatible. The fabrication method allows for control of compressive strength of the IPN hydrogels. The materials are confirmed to be homogeneous at microscopic scales with fluorescent techniques. The IPNs are used for cell encapsulation and have the potential to be used for surface cell culture. The mechanical properties can be adjusted to match those of cardiac tissue. Thus, when combined with the properties of biocompatibility, viable cell encapsulation, and cell culture, the collagenMeHA IPN hydrogels represent a powerful new material for tissue engineering applications.</Abstract>
<Access xmlns="http://purl.org/coar/access_right"
>
</Access>
</Publication>