2026-09-19T16:20:39Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/535432026-06-06T01:03:35Zcom_1721.1_7582com_1721.1_7581com_1721.1_101402col_1721.1_131023col_1721.1_101610
Mahender Singh.
Rimling, Eric C. (Eric Christopher)
Seoh, Wontae Thomas
Massachusetts Institute of Technology. Engineering Systems Division.
Massachusetts Institute of Technology. Engineering Systems Division
2010-04-07T13:39:01Z
2010-04-07T13:39:01Z
2009
2009
http://hdl.handle.net/1721.1/53543
497151365
Thesis (M. Eng. in Logistics)--Massachusetts Institute of Technology, Engineering Systems Division, 2009.
Includes bibliographical references (leaves 77-78).
The pharmaceutical industry creates products which often have more than one supply chain channel, defined as a route through the supply chain network from sourcing to the end market. Each channel's specific cost characteristics are important to the pharmaceutical industry's ability to maintain positive profit margins while meeting high customer service requirements. Determining the optimal supply chain channel involves the analysis of fuel costs, logistics, taxes, wage differences, and many more. Additionally, variables such as time and risk significantly impact the total cost of a supply chain channel, but are extremely difficult to quantify. In this research, we identify the relevant channel costs and variables for the supply chain of a large pharmaceutical corporation. After identification, our study categorizes each cost based on level of measurability and causes of variability to develop a framework identifying the most relevant costs by four product types. We then analyze market forces that affect costs over a product's lifecycle. Finally, we develop an operational model for using the framework to compare costs across multiple supply chain channels and time horizons.
by Eric C. Rimling and Wontae Thomas Seoh.
M.Eng. in Logistics
90 leaves
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by
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http://dspace.mit.edu/handle/1721.1/7582
Engineering Systems Division.
Analysis of global channel costs for the pharmaceutical industry
Thesis
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<Abstract>The pharmaceutical industry creates products which often have more than one supply chain channel, defined as a route through the supply chain network from sourcing to the end market. Each channel's specific cost characteristics are important to the pharmaceutical industry's ability to maintain positive profit margins while meeting high customer service requirements. Determining the optimal supply chain channel involves the analysis of fuel costs, logistics, taxes, wage differences, and many more. Additionally, variables such as time and risk significantly impact the total cost of a supply chain channel, but are extremely difficult to quantify. In this research, we identify the relevant channel costs and variables for the supply chain of a large pharmaceutical corporation. After identification, our study categorizes each cost based on level of measurability and causes of variability to develop a framework identifying the most relevant costs by four product types. We then analyze market forces that affect costs over a product's lifecycle. Finally, we develop an operational model for using the framework to compare costs across multiple supply chain channels and time horizons.</Abstract>
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