2026-09-18T22:53:41Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/580752022-01-13T07:54:29Zcom_1721.1_7582com_1721.1_7581col_1721.1_131022
David K. Gifford.
Danford, Timothy W. (Timothy William), 1979-
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
2010-09-01T16:25:21Z
2010-09-01T16:25:21Z
2010
2010
http://hdl.handle.net/1721.1/58075
631176066
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 95-102).
This thesis presents a computational and algorithmic method for the analysis of high-resolution transcription data in the budding yeast Saccharomyces cerevisiae. We begin by describing a computational system for storing and retrieving spatially-mapped genomic data. This system forms the infrastructure for a novel algorithmic approach to detect and recover instances of same-strand overlapping transcripts in high resolution expression experiments. We then apply these algorithms to a set of transcription experiments in budding yeast, Saccharomyces cerevisiae, in order to identify potential sites of same-strand overlapping transcripts that may be involved in novel forms of transcriptional regulation.
by Timothy Danford.
Ph.D.
102 p.
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
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permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Electrical Engineering and Computer Science.
Dissecting the spatial structure of overlapping transcription in budding yeast
Thesis
application/pdf
Publication
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