2026-09-19T10:10:45Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/695322022-01-13T07:54:36Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Brian W. Anthony.
Namvari, Kasra
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2012-03-01T15:23:07Z
2012-03-01T15:23:07Z
2011
2011
http://hdl.handle.net/1721.1/69532
775603241
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2011.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 90-92).
Electrodes are necessary components for measuring changes in electrical properties in many microfluidic devices. Daktari CD4 Cell Counter system utilizes an interdigitated electrode foil in order to measure the concentration of the CD4 cells in an assay chamber by measuring the impedance drop. Thus the consistency in the dimensions of the interdigitated fingers in the electrode is critical to the repeatability of impedance measurements. This work involved a thorough variation analysis of the electrode dimensions to characterize the repeatability of the new manufacturing process developed by Daktari. For this purpose optical imaging was used to obtain high-resolution images of the electrodes and an algorithm was developed in order to estimate the critical dimensions of interdigitated fingers from the images. The results showed that the dimensional variation in the electrodes had insignificant effect on the performance of the electrodes and that the new manufacturing process is capable of producing satisfactory electrodes within the desired target. The relation between the electrode's dimensional variations was found and the effect of critical process parameters was determined in order to maintain the process statistically in control.
by Kasra Namvari.
M.Eng.
94 p.
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
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http://dspace.mit.edu/handle/1721.1/7582
Mechanical Engineering.
Manufacturability of lab-on-chip devices : dimensional variation analysis of electrode foils using visual technology
Dimensional variation analysis of electrode foils using visual technology
Thesis
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<Abstract>Electrodes are necessary components for measuring changes in electrical properties in many microfluidic devices. Daktari CD4 Cell Counter system utilizes an interdigitated electrode foil in order to measure the concentration of the CD4 cells in an assay chamber by measuring the impedance drop. Thus the consistency in the dimensions of the interdigitated fingers in the electrode is critical to the repeatability of impedance measurements. This work involved a thorough variation analysis of the electrode dimensions to characterize the repeatability of the new manufacturing process developed by Daktari. For this purpose optical imaging was used to obtain high-resolution images of the electrodes and an algorithm was developed in order to estimate the critical dimensions of interdigitated fingers from the images. The results showed that the dimensional variation in the electrodes had insignificant effect on the performance of the electrodes and that the new manufacturing process is capable of producing satisfactory electrodes within the desired target. The relation between the electrode's dimensional variations was found and the effect of critical process parameters was determined in order to maintain the process statistically in control.</Abstract>
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