This is an archived course. A more recent version may be available at ocw.mit.edu.

Calendar

PAS = Prof. Phillip Sharp
RAY = Prof. Richard A. Young

SES # TOPICS LECTURERS
1 Introduction: Nucleus RAY
2 Lecture: Genome RAY
3 Discussion: Genome  
4 Lecture: Cell Cycle Control RAY
5 Discussion: Cell Cycle Control  
6 Lecture: Transcription Apparatus and Regulators RAY
7 Discussion: Transcription Apparatus and Regulators  
8 Lecture: Chromatin and Gene Expression I PAS
9 Discussion: Chromatin and Gene Expression I  
10 Lecture: Chromatin and Gene Expression II RAY
11 Discussion: Chromatin and Gene Expression II  
12 Lecture: Genome Replication/Repair Guest Lecturer: Prof. Angelika Amon
13 Discussion: Genome Replication/Repair  
14 Lecture: Nuclear Structure, Import/Export PAS
15 Discussion: Nuclear Structure, Import/Export  
16 Lecture: DNA Modification/Epigenetics Guest Lecturer: Prof. Rudy Jaenisch
17 Discussion: DNA Modification/Epigenetics  
18 Lecture: Alternative Splicing/Polyadenylation PAS
19 Discussion: Alternative Splicing/Polyadenylation  
20 Lecture: Signal Transduction RAY
21 Discussion: Signal Transduction  
22 Lecture: RNA Interference I - Silencing and microRNAs PAS
23 Discussion: RNA Interference I - Silencing and microRNAs  
24 Lecture: RNA Interference II - Transcription PAS
25 Discussion: RNA Interference II - Transcription  
26 Course Review: Group Discussion