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Now showing items 101-110 of 200
Project process mapping : evaluation, selection, implementation, and assessment of energy cost reduction opportunities in Manufacturing
(Massachusetts Institute of Technology, 2012)
Company X uses large amounts of electricity in its manufacturing operations. Electricity prices at selected plants in the company's Region 1 territory rose by over 350% between 2000 and 2011, in part due to increasing ...
Evaluating future biopharmaceutical inspection needs, infrastructure capability gaps, and technology development strategies
(Massachusetts Institute of Technology, 2012)
The biotechnology industry is undergoing a paradigm shift in the properties of the manufactured drug product. As therapeutic protein formulations change from agonist to antagonist methods of action, the concentration of ...
Corporate sustainability assessment methodology
(Massachusetts Institute of Technology, 2011)
Sustainability is a vague concept specifically in the context of a corporate world. There are numerous definitions for corporate sustainability and just as many ways of evaluating it. This work attempts to define, structure ...
Strategy for reducing the length and variability of aircraft lead time
(Massachusetts Institute of Technology, 2010)
Helicopter manufacturers typically build each aircraft to order, and the lead time for make or buy parts and assemblies can be several months or more. The manufacturers generally have a backlog of orders at any given time, ...
Methods for predicting inventory levels in a segmented retail supply chain
(Massachusetts Institute of Technology, 2015)
Inventory is the largest asset on Nike's balance sheet-$3.9 Billion on May 3 1 st, 2014-and a key indicator of supply chain health. With new markets, products, and channels being added to Nike's sales portfolio each year, ...
Reducing wave cycle time at a multi-channel distribution center
(Massachusetts Institute of Technology, 2018)
Traditional brick and mortar retailers are being forced to adapt as consumer preferences shift towards online shopping. In response, many retailers are developing infrastructure and processes to handle the increased service ...
Analysis and productivity improvement of an automated material handling system through simulation
(Massachusetts Institute of Technology, 2015)
As Amazon.com has grown, the company has invested in warehouse systems similar to those traditionally found in manufacturing. These systems are a complex and interconnected set of manned work processing stations linked ...
Applying constraint-based theory to a complex aerospace manufacturing process
(Massachusetts Institute of Technology, 2015)
A new airplane model is quickly ramping up in production rates, and in order to achieve the organizational targets and commitments, Flow Days, Unit Hours and Cycle Times must be reduced throughout the entire supply chain. ...
Improvement of cleaning effectiveness through Statistical Process Control in active pharmaceutical ingredient (API) manufacturing
(Massachusetts Institute of Technology, 2018)
This thesis presents work that was done to improve the effectiveness of cleaning processes at an active pharmaceutical ingredient (API) manufacturing site that was in the phase of engineering trials and cleaning cycle ...
Investigation of integrally-heated tooling and thermal modeling methodologies for the rapid cure of aerospace composites
(Massachusetts Institute of Technology, 2015)
Carbon Fiber Reinforced Polymer (CFRP) composite manufacturing requires the CFRP part on the associated tool to be heated, cured, and cooled via a prescribed thermal profile. Current methods use large fixed structures such ...