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Reagent usage optimization In high volume diagnostics testing
(Massachusetts Institute of Technology, 2018)
Company X provides healthcare diagnostics testing services. The company competes in the market by providing cost effective, short turn-around-time (TAT) solutions and a large variety of test selections. Reducing operating ...
Optimization of delivery promise policy to control peak demand on a fulfillment network
(Massachusetts Institute of Technology, 2019)
Maintaining high on-time delivery performance is a key objective for Amazon.com and an expectation from customers. This objective is particularly challenging to achieve during periods of peak demand, when extremely high ...
Big data analysis interrogating raw material variability and the impact on process performance
(Massachusetts Institute of Technology, 2019)
Within the biopharmaceutical industry, material sciences is a rapidly growing field to continue to ensure reliable production and delivery of medicines. Consequently, there is an on-going need to evaluate and assess new ...
Separating signal from noise : material demand forecasting and network simulation in a multi-echelon supply chain
(Massachusetts Institute of Technology, 2018)
Mismatches between forecasted and actual demand, for construction, repair and maintenance work in a regulated utility, is a growing risk for the performance of the supply chain. High target service levels and high levels ...
Improving order prioritization for the allocation of constrained supply
(Massachusetts Institute of Technology, 2019)
For top wholesale retail companies, the demand for products from US-based customers (wholesale, digital, and direct to consumer) is extremely high. However, the available supply of a product is contingent upon the success ...
Characterization, prediction, and mitigation of Code Help events at Massachusetts General Hospital
(Massachusetts Institute of Technology, 2019)
This thesis suggests a method to characterize congestion alarms triggered by the Emergency Department (ED) at Massachusetts General Hospital, attempts to predict the incidence of these alarms using logistic regression, and ...
Evaluating the impact of critical product quality attributes on patient outcomes in biologics
(Massachusetts Institute of Technology, 2019)
The primary goal of this project is to link critical product quality attributes in biological medicines with patient outcomes as evidenced by clinical trial data. This project adopts a novel methodology of applying statistical ...
Next generation commercial aircraft engine maintenance, repair, and overhaul capacity planning and gap analysis
(Massachusetts Institute of Technology, 2018)
A critical element in maintaining engine safety and in providing post-production service and support of a commercial aircraft engine is the complete worldwide network of maintenance, repair, and overhaul facilities. Matching ...
Inbound supply chain optimization with ship-mode variation in a fixed-capacity fulfillment center
(Massachusetts Institute of Technology, 2018)
each of the past two years. In order to scale with expected continued sales growth, Amazon has been investing heavily in its inbound supply chain, where product is received and allocated to various nodes, with cross-dock ...
Improving lead time setting and on-time delivery commitments under uncertain supply conditions
(Massachusetts Institute of Technology, 2018)
As Dell seeks to continually improve customer experience, the company is identifying new and innovative ways to improve on-time delivery. Inventory shortages that occur prior to production account for approximately 35% of ...