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Using predictive analytics to address risk in complex supply chains
(Massachusetts Institute of Technology, 2018)
Li & Fung (LF) is a global supply chain manager for consumer product brands and retailers. Worldwide, LF contracts with over 13,000 factories. Frequently, these factories experience incidents, which are internally defined ...
Reducing reworkable discrepancies through standard work for writing inspection instructions and data distribution
(Massachusetts Institute of Technology, 2013)
Each aircraft on the final assembly line inevitably has minor build errors and deviations from the intended design. Errors, like these, that can be corrected on the line are called reworkable discrepancies. Because hundreds ...
Tool selection and kitting : technical and organizational issues
(Massachusetts Institute of Technology, 2013)
Boeing South Carolina builds the Boeing 787 Dreamliner, the world's first composite-skinned wide-body jet. This new manufacturing facility is evolving to meet the demands of building this complex aircraft. One of the ...
Optimizing procurement and handling costs in a utility
(Massachusetts Institute of Technology, 2014)
We propose a novel method to quantify the cost of activities involved in the picking portion of order fulfillment. We adapt the general method of picking cost quantification to the specific situation of TP&G, a publicly ...
Unlocking DC throughput capacity through improved flow
(Massachusetts Institute of Technology, 2018)
The large multi-channel apparel distribution center was built as a purely wholesale building in the 1900s. With distribution becoming more complex due to e-commerce and smaller orders for more frequent replenishment, the ...
Optimizing the internal reuse of wireless network equipment
(Massachusetts Institute of Technology, 2013)
Reusing high-value wireless network equipment can allow telecommunications providers to achieve both financial and environmental benefits. However, without standardized processes and tools to reuse equipment, the reuse ...
Development of a risk management system for consumables used in biopharmaceutical manufacturing
(Massachusetts Institute of Technology, 2013)
Injectable drugs, like those manufactured by the BioPharmOps group of Novartis Pharmaceuticals AG, must conform to strict guidelines for purity and potency. Recent non-conformances of critical supplied consumables have ...
Managing expectations during acquisition of bespoke automation systems
(Massachusetts Institute of Technology, 2016)
A new facility seeks to manufacture inlets for the turbine of the new NDA aircraft. The inlet is a new design and has never been built before. To complicate matters the manufacturer, Aeron 2 Company, has not traditionally ...
Evaluation of postponement in the Drug Product supply chain
(Massachusetts Institute of Technology, 2015)
This thesis evaluates the use of postponement in the Drug Product (DP) supply chain at Amgen, which is characterized by highly variable production lead times. The motivation for the use of postponement in the DP supply ...
Augmenting drug process development capacity through applications of lean principles and high throughput technology
(Massachusetts Institute of Technology, 2018)
The long development lead time and high R&D costs for biologics drugs makes it imperative to eliminate delays and inefficiencies. Limited process development capacity can lead to delays in the availability of life-saving ...