Browsing Synthetic Biology by Title

Now showing items 122-139 of 139

    • Should We Synthesize A Human Genome? 

      Endy, Drew; Zoloth, Laurie (2016-05-10)
      Given that human genome synthesis is a technology that could be used to completely redefine the core of what now joins all of humanity together as a species, we argue that discussions of making such capacities real, like ...

    • Simulation, Models, and Refactoring of Bacteriophage T7 

      Kosuri, Sriram (2007-02-02)
      Our understanding of why biological systems are designed in a particular way would benefit from biophysically-realistic models that can make accurate predictions on the time-evolution of molecular events given arbitrary ...

    • Software files to support thesis of Ty Thomson 

      Thomson, Ty (2008-05-21)

    • Standard Biological Part Automatic Modeling Database Language (MoDeL) 

      Wang, Zhen; Liao, Chen; Jiang, Hao; Yao, Xiaomo; Jiang, Kun (2010-11-09)
      This BioBricks Foundation Request for Comments (BBF RFC) describes the Standard Biological Part Automatic Modeling Database Language (MoDeL). MoDeL provides a language and syntax standard for automatic modeling databases ...

    • Standard for Synthesis of Customized Peptides by Non-Ribosomal Peptide Synthetases 

      Beer, Ralf; Christiansen, Tania; Herbst, Konrad; Ignatiadis, Nikos; Kats, Ilia; e.a. (2013-10-04)
      The purpose of this RFC is to introduce a standardized framework for the engineering of customizable non-ribosomal peptide synthetases (NRPS) and their application for in vivo and in vitro synthesis of short non-ribosomal ...

    • Standard for the Electronic Distribution of SBOLv Diagrams 

      Johnson, Jeffrey; Galdzicki, Michal; Sauro, Herbert M (2010-12-05)
      A common method for publicly distributing design diagrams on the Web would enhance understanding of the mechanisms and intended function of synthetic DNA constructs. We aim to improve the usefulness of the depicted design ...

    • A Standard Parts List for Biological Circuitry 

      Arkin, Adam P; Endy, Drew (DARPA White Paper, 1999-10-07)
      One of the hallmarks of biochemical circuits found in nature is analog, asymmetric, asynchronous design. That is, there is little standardization of parts, e.g. all the promoters have different strengths and kinetics, ...

    • Strategy for Biological Risk & Security 

      Endy, Drew (2003-10)
      Why do biological risks exist? Can we develop and implement a strategy for thoughtfully approaching future biological risks? This short, working report provides an abstract introduction to the problem of biological risk ...

    • Synthetic Biology Open Language (SBOL) Version 1.1.0 

      Galdzicki, Michal; Wilson, Mandy; Rodriguez, Cesar A.; Pocock, Matthew R.; Oberortner, Ernst; e.a. (2012-10-11)
      In this BioBricks Foundation Request for Comments (BBF RFC), we specify the Synthetic Biology Open Language (SBOL) Version 1.1.0 to enable the electronic exchange of information describing DNA components used in synthetic ...

    • Synthetic Biology Open Language Visual (SBOL Visual), version 1.0.0 

      Quinn, Jacqueline; Beal, Jacob; Bhatia, Swapnil; Cai, Patrick; Chen, Joanna; e.a. (2013-03-31)
      In this BioBricks Foundation Request for Comments (BBF RFC), we specify the Synthetic Biology Open Language Visual standard (SBOL Visual) to enable consistent, human-readable depiction of genetic designs.

    • SYNTHETIC BIOLOGY: CAUGHT BETWEEN PROPERTY RIGHTS, THE PUBLIC DOMAIN, AND THE COMMONS 

      Rai, Arti; Boyle, James (2006-11-05)

    • Synthetic Genomics: Options for Governance 

      Garfinkel, Michele; Endy, Drew; Epstein, Gerald; Friedman, Robert (2007-10-17)
      Gene and genome synthesis, that is, constructing long stretches of DNA from constituent chemicals, provides scientists with new and unparalleled capabilities both for understanding biology and for using it for beneficial ...

    • Synthetic Viral Genomics: Risks and Benefits for Science and Society 

      Baric, Ralph (2007-12-04)
      Viral disease outbreaks have long inspired fear in human populations. Highly pathogenic infectious disease has shaped world history, primarily by impacting the outcome of wars and other global conflicts and precipitating ...

    • Title: Synthetic Biology Open Language (SBOL) Version 1.0.0 

      Wipat, Anil; Villalobos, Alan; Stan, Guy-Bart; Smith, Trevor; Sauro, Herbert; e.a. (2011-10-03)
      In this BioBricks Foundation Request for Comments (BBF RFC), we specify the Synthetic Biology Open Language (SBOL) Version 1.0.0 to enable the electronic exchange of information describing DNA components used in synthetic ...

    • Units for Promoter Measurement in Mammalian Cells 

      Velten, Lars; Iwamoto, Nao; Hiller, Corinna; Uckelmann, Hannah; Zhu, Chenchen; e.a. (2009-10-21)
      The purpose of this RFC is to provide units for the characterization of promoter strength for use in mammalian cells. RMPU is mRNA based and directly proportional to PoPS, whereas REU is protein based and not proportional ...

    • The USER cloning standard 

      Kaas, Christian Schrøder; Hansen, Niels Bjørn; Genee, Hans Jasper; Olsen, Lars Rønn; Matos, Cláudia; e.a. (2009-11-01)
      This BioBricks Foundation Request for Comments (BBF RFC) provides information about the design of uracil-containing primers used for USER cloning and USER fusion.

    • Working Papers for Synthetic Genomics: Risks and Benefits for Science and Society 

      Garfinkel, Michele; Endy, Drew; Epstein, Gerald; Friedman, Robert (2007-12-04)
      The following papers were commissioned for the project Synthetic Genomics: Risks and Benefits for Science and Society. These papers formed the basis of many discussions at project workshops and at a large invitational ...

    • Yeast Golden Gate: Standardized Assembly of S. cerevisiae Transcriptional Units 

      Boeke, Jef; Mitchell, Leslie; Cai, Yizhi; Stracquadanio, Giovanni; Chuang, James; e.a. (2012-10-11)
      BBF RFC 88 describes a new standard for the assembly of basic Saccharomyces cerevisiae transcriptional units (TUs) consisting of a promoter/5’untranslated region (UTR), open reading frame (ORF), and 3’UTR/terminator. Note ...