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Vertical integration and strategic sourcing in the biopharmaceutical industry

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dc.contributor.advisor Charles L. Cooney and Donald B. Rosenfield. en_US
dc.contributor.author Haupt, Lynne Felice en_US
dc.contributor.other Leaders for Manufacturing Program. en_US
dc.date.accessioned 2006-11-08T16:45:13Z
dc.date.available 2006-11-08T16:45:13Z
dc.date.copyright 2005 en_US
dc.date.issued 2005 en_US
dc.identifier.uri http://hdl.handle.net/1721.1/34827
dc.description Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering; in conjunction with the Leaders for Manufacturing Program at MIT, 2005. en_US
dc.description Includes bibliographical references (p. 77-78). en_US
dc.description.abstract Biopharmaceutical companies are focusing on operational efficiency more than ever before due to cost pressures, generic competition, complex pricing, regulations, and globalization. Due to the low probabilities of success of drug development and achieving market penetration, it is critical for a company to optimize the sizing of a manufacturing facility to achieve maximum capacity utilization while avoiding or minimizing non-productive, idle capacity. In order to achieve high manufacturing efficiency and minimize capital risks, many firms elect to outsource various phases of the drug development value chain. This thesis investigates the major drivers for vertical integration and outsourcing in the biopharmaceutical industry. This work examines outsourcing and vertical integration decisions including their financial, organizational, and strategic effects on the organization. It presents a methodology and framework for strategic sourcing decisions and includes a set of quantitative tools for assessing outsourcing options and guidelines for selecting, implementing, and managing relationships with contract manufacturers. These frameworks are applied to case studies conducted at the Genzyme Corporation. The strategic sourcing decisions tools developed in this work are highly customizable and can be adopted by other companies in the biopharmaceutical industry. en_US
dc.description.statementofresponsibility by Lynne Felice Haupt. en_US
dc.format.extent 78 p. en_US
dc.format.extent 4350153 bytes
dc.format.extent 4353420 bytes
dc.format.mimetype application/pdf
dc.format.mimetype application/pdf
dc.language.iso eng en_US
dc.publisher Massachusetts Institute of Technology en_US
dc.rights M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. en_US
dc.rights.uri http://dspace.mit.edu/handle/1721.1/7582
dc.subject Mechanical Engineering. en_US
dc.subject Sloan School of Management. en_US
dc.subject Leaders for Manufacturing Program. en_US
dc.title Vertical integration and strategic sourcing in the biopharmaceutical industry en_US
dc.type Thesis en_US
dc.description.degree S.M. en_US
dc.description.degree M.B.A. en_US
dc.contributor.department Massachusetts Institute of Technology. Dept. of Mechanical Engineering. en_US
dc.contributor.department Sloan School of Management. en_US
dc.contributor.department Leaders for Manufacturing Program. en_US
dc.identifier.oclc 61670866 en_US


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