NIR-Sensitive Au-Au₂S Nanoparticles for Drug Delivery

dc.contributor.author	Ren, L.
dc.contributor.author	Chow, Gan-Moog
dc.date.accessioned	2003-12-08T15:31:48Z
dc.date.available	2003-12-08T15:31:48Z
dc.date.issued	2003-01
dc.identifier.uri	http://hdl.handle.net/1721.1/3787
dc.description.abstract	Near IR (NIR) sensitive Au-Au₂S nanoparticles were prepared by mixing HAuCl₄ and Na₂S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au₂S nanoparticle surface via the 11-mercaptoundecanoic acid layers. The results showed that the degree of adsorption of cis-platin onto Au-Au₂S nanoparticles was controlled by the pH value of solution, and the drug release was sensitive to NIR irradiation. The cis-platin loaded Au-Au₂S nanoparticles can be potentially applied as NIR activated drug delivery carrier.	en
dc.description.sponsorship	Singapore-MIT Alliance (SMA)	en
dc.format.extent	101640 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en_US
dc.relation.ispartofseries	Molecular Engineering of Biological and Chemical Systems (MEBCS);
dc.subject	drug delivery	en
dc.subject	near-infrared	en
dc.subject	Au-Au2	en
dc.subject	nanoparticles	en
dc.subject	cis-Platin	en
dc.title	NIR-Sensitive Au-Au₂S Nanoparticles for Drug Delivery	en
dc.type	Article	en