Targeted read-out, analysis, and control to elucidate dynamic-emotional processing

Abstract

Many psychological disorders, such as panic disorder, are episodic in nature, with unpredictable onsets and similarly unpredictable durations. That the severe symptoms of these disorders come in waves rather than remain at a level of stasis poses a daunting challenge for pharmacological approaches that lack temporal precision. Here, a set of technologies and approaches for examining and treating these conditions are developed, using techniques to monitor brain activity and shut down specific brain sub-regions at times critical to the recall of emotional memory.