Browsing MIT Theses by Title
Now showing items 35113-35132 of 61728
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Mechanism and assessment of spin transfer torque (STT) based memory
(Massachusetts Institute of Technology, 2009)When a sufficient current density passes through the MTJ, the spin-polarized current will exert a spin transfer torque to switch the magnetization of the free layer. This is the fundamental of the novel write mechanism in ... -
Mechanism and Biological Scope of Target-Directed MicroRNA Degradation
(Massachusetts Institute of Technology, 2023-02)MicroRNAs (miRNAs) are small, ~21 nucleotide RNAs that guide Argonaute (AGO) proteins to complementary target RNAs using base-pairing interactions. In canonical miRNA-mediated repression, AGO recruits repressive trans-acting ... -
Mechanism and consequences of Mu transpososome remodeling by the ClpX chaperone
(Massachusetts Institute of Technology, 2003)E. coli ClpX is a member of the Clp/Hsp100 family of ATPases that remodel multi-component complexes and facilitate ATP-dependent protein degradation. Protein remodelers alter the biological activity of their substrates, ... -
The mechanism and function of pervasive noncoding transcription in the mammalian genome
(Massachusetts Institute of Technology, 2014)The vast majority of the mammalian genome does not encode proteins. Only 2% of the genome is exonic, yet recent deep survey of human transcripitome suggested that 75% of the genome is transcribed, including half of the ... -
Mechanism and importance of Mcm2-7 double-hexamer formation during DNA replication initiation
(Massachusetts Institute of Technology, 2019)All cells must duplicate their genome completely and accurately in each cell cycle. Thus, DNA replication is a highly-regulated multi-step process that ensures the genome is duplicated only once per cell cycle. In eukaryotic ... -
Mechanism and specificity of bacterial two-component signaling systems
(Massachusetts Institute of Technology, 2010)Bacterial two component signaling (TCS) systems are the predominant means by which bacteria sense and respond to external signals. These systems represent a large family of paralogous proteins; often hundreds of the histidine ... -
Mechanism by which surfactants modify adipic acid crystal growth rate and habit
(Massachusetts Institute of Technology, 1961) -
Mechanism design : a new algorithmic framework
(Massachusetts Institute of Technology, 2013)A modern engineering system, e.g. the Internet, faces challenges from both the strategic behavior of its self-interested participants and the inherent computational intractability of large systems. Responding to this ... -
Mechanism design : from optimal transport theory to revenue maximization
(Massachusetts Institute of Technology, 2017)A central problem in Economics and Algorithmic Game Theory is the design of auctions that maximize the auctioneer's expected revenue. While optimal selling of a single item has been well-understood since the pioneering ... -
Mechanism design of a multi-motion automobile door
(Massachusetts Institute of Technology, 2008)This thesis describes the design and prototype construction of a multi-motion automobile door. This design is intended to provide a unique option for the opening of an automobile by enabling the door to open in two separate ... -
Mechanism design with approximate types
(Massachusetts Institute of Technology, 2012)In mechanism design, we replace the strong assumption that each player knows his own payoff type exactly with the more realistic assumption that he knows it only approximately: each player i only knows that his true type ... -
Mechanism design with set-theoretic beliefs
(Massachusetts Institute of Technology, 2012)In settings of incomplete information, we put forward: (1) a very conservative - indeed, purely set-theoretic- model of the beliefs (including totally wrong ones) that each player may have about the payoff types of his ... -
Mechanism for actuating seaweed harvesting device
(Massachusetts Institute of Technology, 2019)Mechanical systems to automate a critical aspect of the seaweed farming process were designed and iterated to determine their feasibility as a substitute for human labor on a commercial large-scale seaweed farm. This paper ... -
A mechanism for testing the torsional mechanics of origami-inspired hinges
(Massachusetts Institute of Technology, 2015)Folding 2-dimensional sheets into static and dynamic 3-dimensional structures has the potential to improve rate, cost, and flexibility in manufacturing. In order to explore origami-inspired design, a better understanding ... -
Mechanism of acquired temozolomide resistance in glioblastoma
(Massachusetts Institute of Technology, 2014)Glioblastoma (GBM) is the most common and malignant form of brain cancer. After aggressive treatment, therapy resistant tumors inevitably recur. However, the molecular mechanisms underlying such resistance remain unclear. ... -
Mechanism of active substrate delivery by the AAA+ protease adaptor CIpS
(Massachusetts Institute of Technology, 2015)AAA+ molecular machines power myriad cellular processes including protein degradation, microtubule severing, membrane fusion, and initiation of DNA replication. Protein quality control in all organisms involves deployment ... -
Mechanism of aggregation of oxidation-mimicking mutants of human [gamma]D-crystallin
(Massachusetts Institute of Technology, 2016)Protein misfolding and aggregation is a ubiquitous challenge in biology and medicine. Among its many manifestations is age-onset cataract disease, the leading cause of vision loss. Cataracts arise from increased light ... -
Mechanism of assembly of the tyrosyl radical-diiron(III) cofactor of E. coli ribonucleotide reductase
(Massachusetts Institute of Technology, 1996) -
Mechanism of attenuation of compressional and shear waves for dry, water and benzene satruated rocks
(Massachusetts Institute of Technology, 1985) -
Mechanism of biosynthesis of the dimanganese-tyrosyl radical cofactor of class lb Ribonucleotide reductase
(Massachusetts Institute of Technology, 2012)Ribonucleotide reductases (RNRs) catalyze the reduction of nucleotides to deoxynucleotides in all organisms. The class Ia and lb RNRs comprise two subunits: a2 contains the site of nucleotide reduction, and p2 contains an ...
