Class Description
This course presents the information that has been collected from studying genetic variation in model systems like nematode and drosophila for mutation studies. Also, new tools that are available to manipulate gene expression, and genes of interest in specific regions of the brain, will be presented. Some of these manipulations are at the ionic channel level, while others are at the organism level. By changing gene expression patterns during development through knockouts, conditional knockouts, or overexpression, the changes in the system can be explored. Diseases that are the result of loss of expression or missing genes in humans will also be studied.
Requirements
Attendance
Two presentations
Paper summaries
Term paper
Final exam
Details of the course requirements are described on the assignments page.