Syllabus

The course material will focus on the basic principles of biophysics, biochemistry and physiology related to drug action and interaction, distribution, metabolism and toxicity. The course will consist of lectures, a clinical demonstration session at Massachusetts General Hospital, and lecturer- and student-led case discussions.

HST students taking this course will be graded on an Excellent, Satisfactory, Unsatisfactory basis. The grade of Marginally Satisfactory may also be given in borderline cases. HST (or HMS) M.D. student grades will be recoded as Pass/Fail. Student evaluations will be based on written homework, classroom work and oral presentations, as well as the midterm and final examinations.

Required

Katzung, B. ed. Basic and Clinical Pharmacology. 8th ed. New York: McGraw-Hill, 2001.

Optional

Hardman, J. G. ed. The Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw-Hill, 2001.
"G&G" (named for the original editors, Goodman and Gilman) is an excellent reference many of you will want on your shelves. New editions have been coming out at roughly five year intervals.