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Co-evolution and Co-speciation of Host-Gut Bacteria Systems
Name
1-s2.0-S1931312820303541-main.pdf
Description
Published version
Size
1.06 MB
Format
Adobe PDF
Checksum (MD5)
3a50703b93075b7a7c9575f60d5cf3e8
Author(s)
Groussin, Mathieu
Mazel, Florent
Alm, Eric J
Date Issued
2020
Journal
Cell Host and Microbe
Publisher
Elsevier BV
Version
Final published version
Abstract
© 2020 The Authors Mammalian gut microbiomes profoundly influence host fitness, but the processes that drive the evolution of host-microbiome systems are poorly understood. Recent studies suggest that mammals and their individual gut symbionts can have parallel evolutionary histories, as represented by their congruent phylogenies. These “co-phylogenetic” patterns are signatures of ancient co-speciation events and illustrate the cohesiveness of the mammalian host-gut microbiome entity over evolutionary times. Theory predicts that co-speciation between mammals and their gut symbionts could result from their co-evolution. However, there is only limited evidence of such co-evolution. Here, we propose a model that explains cophylogenetic patterns without relying on co-evolution. Specifically, we suggest that individual gut bacteria are likely to diverge in patterns recapitulating host phylogeny when hosts undergo allopatric speciation, limiting inter-host bacterial dispersal and genomic recombination. We provide evidence that the model is empirically grounded and propose a series of observational and experimental approaches to test its validity.
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
10.1016/J.CHOM.2020.06.013
