Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing

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Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing

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sword-2021-03-24T17:26:23.original.xml (130 B)

Original SWORD entry document

Date Issued

November 14, 2019

Journal

Cell

Publisher

Elsevier BV

Version

Final published version

Abstract

A high-throughput method for amplication-free single-cell whole-genome sequencing can be scaled up to analyze tens of thousands of cells from different tissues and clinical sample types and identifies replication states, aneuploidies, and subclonal mutations.

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Creative Commons Attribution-NonCommercial-NoDerivs License

http://creativecommons.org/licenses/by-nc-nd/4.0/

Persistent DSpace Link

https://hdl.handle.net/1721.1/136528

DOI of Published Version

10.1016/j.cell.2019.10.026