dc.contributor.advisor | Daniel Anderson. | en_US |
dc.contributor.author | Bader, Andrew R. | en_US |
dc.contributor.other | Massachusetts Institute of Technology. Department of Mechanical Engineering. | en_US |
dc.date.accessioned | 2020-09-15T22:01:22Z | |
dc.date.available | 2020-09-15T22:01:22Z | |
dc.date.copyright | 2020 | en_US |
dc.date.issued | 2020 | en_US |
dc.identifier.uri | https://hdl.handle.net/1721.1/127505 | |
dc.description | Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, May, 2020 | en_US |
dc.description | Cataloged from the official PDF of thesis. | en_US |
dc.description | Includes bibliographical references (pages 63-97). | en_US |
dc.description.abstract | Significant progress has been made in the field of biomaterials for non-viral delivery of macromolecules. A wide variety of distinct types of novel biomaterials, in combination with corresponding cutting-edge therapeutic systems and technologies, have been developed and have shown highly promising therapeutic efficacies in research studies published. Furthermore, a number of these technologies are rapidly progressing to and through clinical trial. Specifically, substantial progress related to the development of drug delivery technologies including lipid nanoparticulate formulations, polymer nanoparticulate formulations, and other types of nanoparticulate formulations may lead to the development of substantial libraries of novel, highly effective, next-generation therapeutic technologies. The motivation of this thesis is to review these state-of-the-art technologies. | en_US |
dc.description.statementofresponsibility | by Andrew R. Bader. | en_US |
dc.format.extent | 97 pages ; | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Massachusetts Institute of Technology | en_US |
dc.rights | MIT theses may be protected by copyright. Please reuse MIT thesis content according to the MIT Libraries Permissions Policy, which is available through the URL provided. | en_US |
dc.rights.uri | http://dspace.mit.edu/handle/1721.1/7582 | en_US |
dc.subject | Mechanical Engineering. | en_US |
dc.title | Biomaterials for non-viral delivery of nucleic acid drugs | en_US |
dc.type | Thesis | en_US |
dc.description.degree | S.M. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Mechanical Engineering | en_US |
dc.identifier.oclc | 1193027179 | en_US |
dc.description.collection | S.M. Massachusetts Institute of Technology, Department of Mechanical Engineering | en_US |
dspace.imported | 2020-09-15T22:01:22Z | en_US |
mit.thesis.degree | Master | en_US |
mit.thesis.department | MechE | en_US |