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Inhibiting HIV-1 entry : utilizing a transient intermediate of viral membrane fusion as a target for drug discovery
(Massachusetts Institute of Technology, 2000)
In order to reproduce, enveloped viruses must deposit their genomes into host cells. The first step of this process is the fusion of viral and cellular membranes, which allows the release of the viral contents into the ...
Trace metals and the ecology of marine cyanobacteria
(Massachusetts Institute of Technology, 2000)
The marine cyanobacteria Synechococcus and Prochlorococcus are important primary producers in oligotrophic oceans. The abundance and cell division rates of these cyanobacteria can be influenced by trace metals such as iron ...
The human Deleted in Azoospermia gene family : structure, function and evolution
(Massachusetts Institute of Technology, 2000)
The human Deleted in Azoospermia genes lie within the AZFc region of the Y chromosome that is frequently deleted in men with severe spermatogenic failure and male infertility. This thesis describes the evolution, structure ...