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dc.contributor.authorAshford, Nicholas A.
dc.date.accessioned2021-06-24T21:24:27Z
dc.date.available2021-06-24T21:24:27Z
dc.date.issued2005
dc.identifier.urihttps://hdl.handle.net/1721.1/131041
dc.description.abstractHuman monitoring in the workplace, sometimes referred to as medical screening, is a collation of practices that focuses on the workers as an indicator that: 1) disease may result on exposure to a toxic substance, radiation, or other traumas (medical surveillance); 2) a toxic substance has been absorbed into the body (biological monitoring); 3) a particular worker may be especially predisposed to disease (genetic screening or other probes of sensitivity); and 4) a pre-clinical disease state exists, indicating that potentially harmful exposure has occurred (genetic monitoring). These monitoring practices, especially when required or carried out by a government agency or the employer, raise serious and complex scientific, legal, and ethical concerns. This article focuses on the practice of “genetic testing” that involves mainly types 3 and 4, i.e., those involving both genetic screening for predisposition to disease, and genetic monitoring for indications of potential harm due to workplace exposure. However, the other two types of monitoring may also be relevant. The article also constructs a philosophic framework for: 1) examining the adequacy of law as an embodiment of ethical values, and sound science, concerning the genetic testing of workers; and 2) identifying possible solutions to the attendant legal and moral dilemmas. In the workplace, the analysis necessarily focuses on three sets of activities involving distinct participants: workers, employers, corporations, physicians – either in-house or under contract – and the government. The sets of activities deserving separate consideration are: 1) requiring the worker to submit to monitoring tests; 2) disseminating the results of the tests; and 3) using the test results. Because the different kinds of monitoring address different stages of the pathway from exposure to disease, and because what is monitored affects different groups of workers differently, specification of exemplar problems and a case-by-case analysis are essential, lest we face useless generalities at the end.en_US
dc.language.isoen_USen_US
dc.publisherEuropean Journal of Oncology Libraryen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.titleScientific, ethical and legal challenges in work-related genetic testing in the United Statesen_US
dc.typeArticleen_US


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