7.342 Personal Genomics and Medicine: What's in Your Genome?, Spring 2014

Author(s)
Herskovits, A. Zara
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Alternative title
Personal Genomics and Medicine: What's in Your Genome?
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Abstract
Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Date issued
2014-06
URI
https://hdl.handle.net/1721.1/148353
Department
Massachusetts Institute of Technology. Department of Biology
Other identifiers
7.342-Spring2014
Other identifiers
7.342
IMSCP-MD5-a6926e9560714a4b13899069a959f41b
Keywords
genome sequencing, genome analysis, disease susceptibility, drug metabolism, human ancestry, mitochondrial DNA, tyrosine kinase inhibitors, BCR-ABL gene fusion, PCSK9 inhibitors, hypercholesterolemia, genetic testing, next generation sequencing, Single-nucleotide polymorphisms (SNPs), copy number variations (CNVs), genome-wide association studies (GWAS), Chronic myelogenous leukemia (CML), mosaics, chimeras, bioinformatics
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