7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance, Spring 2004

Author(s)
Halme, Dina Gould
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Alternative title
Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance
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Abstract
Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.
Date issued
2004-06
URI
https://hdl.handle.net/1721.1/148362
Department
Massachusetts Institute of Technology. Department of Biology
Other identifiers
7.340-Spring2004
Other identifiers
7.340
IMSCP-MD5-aa7f926250a6625b662486dc7bd1efc9
Keywords
immunology, immune system, immune evasion, pathogen, effector function, infections, Human cytomegalovirus, Human Immunodeficiency Virus, CD4 cells, CD8 cells, T cells, surace receptors, cell lysis, host-pathogen interactions, host surveillance, antibodies, MHC class I, blood-borne pathogens, macrophages, phagocytosis, endocytosis, degradation, antigen, apoptosis, cytokines, immune response
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