7.340 Avoiding Genomic Instability: DNA Replication, the Cell Cycle, and Cancer, Fall 2006
Author(s)
Randell, John; Tanny, Robyn
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Alternative title
Avoiding Genomic Instability: DNA Replication, the Cell Cycle, and Cancer
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In this class we will learn about how the process of DNA replication is regulated throughout the cell cycle and what happens when DNA replication goes awry. How does the cell know when and where to begin replicating its DNA? How does a cell prevent its DNA from being replicated more than once? How does damaged DNA cause the cell to arrest DNA replication until that damage has been repaired? And how is the duplication of the genome coordinated with other essential processes? We will examine both classical and current papers from the scientific literature to provide answers to these questions and to gain insights into how biologists have approached such problems. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Date issued
2006-12Other identifiers
7.340-Fall2006
Other identifiers
7.340
IMSCP-MD5-cc32efb7776e474593468796a38c2221
Keywords
cell, genetic material, cell death, tumorigenesis, mutations, genes, DNA replication, cell cycle, damaged DNA, genome, tumor formation, anti-cancer drugs, viruses, cellular controls
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