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Editorial: Mechanobiology of organoid systems

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Author(s)
He, Shijie
•
Mierke, Claudia Tanja
•
Sun, Yubing
•
Eyckmans, Jeroen
•
Guo, Ming
Date Issued
January 30, 2024
Journal
Frontiers in Cell and Developmental Biology
Publisher
Frontiers Media SA
Citation
He S, Mierke CT, Sun Y, Eyckmans J and Guo M (2024) Editorial: Mechanobiology of organoid systems. Front. Cell Dev. Biol. 12:1369713.
Version
Final published version
Abstract
Seminal studies in the mid 2000s reported that extracellular matrix (ECM) stiffness (Engler et al., 2006), cell shape and cellular contractility (McBeath et al., 2004) can direct mesenchymal stem cell differentiation. During the subsequent 20 years, the field of mechanobiology has been significant inspired and substantially developed. These studies helped to better understand how mechanical forces regulate complex cell behaviors and tissue functions (Han et al., 2018; Li et al., 2021a; Li et al., 2021b), and influence homeostasis and disease development (Chowdhury et al., 2021).
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Creative Commons Attribution
https://creativecommons.org/licenses/by/4.0/
Persistent DSpace Link
https://dspace.mit.edu/handle/1721.1/176554
DOI of Published Version
https://doi.org/10.3389/fcell.2024.1369713
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