Publications
Recent Submissions
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A Mechanistic Model of the Actin Cycle
(Biophysical Society, 2004-05)We have derived a broad, deterministic model of the steady-state actin cycle that includes its major regulatory mechanisms. Ours is the first model to solve the complete nucleotide profile within filaments, a feature that ... -
Simultaneous Measurements of Actin Filament Turnover, Filament Fraction, and Monomer Diffusion in Endothelial Cells
(Biophysical Society, 1998-09)The analogous techniques of photoactivation of fluorescence (PAF) and fluorescence recovery after photobleaching (FRAP) have been applied previously to the study of actin dynamics in living cells. Traditionally, ... -
Theoretical Estimates of Mechanical Properties of the Endothelial Cell Cytoskeleton
(Biophysical Society, 1996)Current modeling of endothelial cell mechanics does not account for the network of F-actin that permeates the cytoplasm. This network, the distributed cytoplasmic structural actin (DCSA), extends from apical to basal ...