Publications

Recent Submissions

  • A Mechanistic Model of the Actin Cycle 

    Bindschadler, M.; Osborn, E. A.; Dewey, C. F. Jr; McGrath, J. L. (Biophysical Society, 2004-05)
    We have derived a broad, deterministic model of the steady-state actin cycle that includes its major regulatory mechanisms. Ours is the first model to solve the complete nucleotide profile within filaments, a feature that ...

  • Simultaneous Measurements of Actin Filament Turnover, Filament Fraction, and Monomer Diffusion in Endothelial Cells 

    McGrath, J. L.; Tardy, Y.; Dewey, C. F. Jr; Meister, J. J.; Hartwig, J. H. (Biophysical Society, 1998-09)
    The analogous techniques of photoactivation of fluorescence (PAF) and fluorescence recovery after photobleaching (FRAP) have been applied previously to the study of actin dynamics in living cells. Traditionally, ...

  • Theoretical Estimates of Mechanical Properties of the Endothelial Cell Cytoskeleton 

    Satcher, Robert L. Jr.; Dewey, C. Forbes Jr. (Biophysical Society, 1996)
    Current modeling of endothelial cell mechanics does not account for the network of F-actin that permeates the cytoplasm. This network, the distributed cytoplasmic structural actin (DCSA), extends from apical to basal ...

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