Browsing MIT Open Access Articles by Author "Labaree, David"
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Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using “click” chemistry
Hanson, Robert N.; Hua, Edward; Labaree, David; Hochberg, Richard B.; Proffitt, Kyle; e.a. (Royal Society of Chemistry, 2012-09)A convergent synthesis of a novel estrogen receptor-targeted drug hybrid was developed based on structures of the potent anti-proliferative mitomycin C and the steroidal anti-estrogen RU 39411. The steroidal antiestrogen ...