Browsing MIT Open Access Articles by Author "Labade, Ajay S"

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    • Advances in Chromatin and Chromosome Research: Perspectives from Multiple Fields 

      Agbleke, Andrews Akwasi; Amitai, Assaf; Buenrostro, Jason D; Chakrabarti, Aditi; Chu, Lingluo; e.a. (Elsevier BV, 2020)
      © 2020 Elsevier Inc. Nucleosomes package genomic DNA into chromatin. By regulating DNA access for transcription, replication, DNA repair, and epigenetic modification, chromatin forms the nexus of most nuclear processes. ...

    • In situ genome sequencing resolves DNA sequence and structure in intact biological samples 

      Payne, Andrew C; Chiang, Zachary D; Reginato, Paul L; Mangiameli, Sarah M; Murray, Evan M; e.a. (American Association for the Advancement of Science (AAAS), 2020-12)
      Understanding genome organization requires integration of DNA sequence and three-dimensional spatial context; however, existing genome-wide methods lack either base pair sequence resolution or direct spatial localization. ...