| dc.contributor.author | Yannas, Ioannis | en_US |
| dc.contributor.author | Spector, Myron | en_US |
| dc.coverage.temporal | Fall 2003 | en_US |
| dc.date.issued | 2003-12 | |
| dc.identifier | 20.441-Fall2003 | |
| dc.identifier | local: 20.441 | |
| dc.identifier | local: 2.79J | |
| dc.identifier | local: 3.96J | |
| dc.identifier | local: HST.522J | |
| dc.identifier | local: IMSCP-MD5-e1af5d3c45e1048ac71d66822814879f | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/67471 | |
| dc.description.abstract | This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Also addressed are criteria for restoration of physiological function for tissues and organs. | en_US |
| dc.language | en-US | en_US |
| dc.relation | | en_US |
| dc.rights.uri | Usage Restrictions: This site (c) Massachusetts Institute of Technology 2011. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. | en_US |
| dc.subject | medical implants | en_US |
| dc.subject | artificial organs | en_US |
| dc.subject | tissue engineering | en_US |
| dc.subject | matrix | en_US |
| dc.subject | biomaterials | en_US |
| dc.subject | protein adsorption | en_US |
| dc.subject | unit cell process | en_US |
| dc.subject | wound healing | en_US |
| dc.subject | tissue remodeling | en_US |
| dc.subject | tissue regeneration | en_US |
| dc.subject | organ regeneration | en_US |
| dc.subject | prosthesis | en_US |
| dc.subject | biodegradable | en_US |
| dc.subject | bioreplaceable implants | en_US |
| dc.subject | BE.441 | en_US |
| dc.subject | 2.79J | en_US |
| dc.subject | 3.96J | en_US |
| dc.subject | HST.522J | en_US |
| dc.subject | 2.79 | en_US |
| dc.subject | 3.96 | en_US |
| dc.subject | HST.522 | en_US |
| dc.title | 20.441 / 2.79J / 3.96J / HST.522J Biomaterials-Tissue Interactions (BE.441), Fall 2003 | en_US |
| dc.title.alternative | Biomaterials-Tissue Interactions (BE.441) | en_US |
