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Now showing items 11-20 of 41
Lean transformation of a supply chain organization
(Massachusetts Institute of Technology, 2008)
There are two basic schools of thought regarding how to approach a Lean transformation. Either start with introducing Lean tools or start with driving a Lean cultural change. Academic researchers like Steve Spear (Harvard/MIT), ...
Investigating late stage biopharmaceutical product loss using novel analytical and process technology
(Massachusetts Institute of Technology, 2008)
The biopharmaceutical industry uses recombinant protein technologies to provide novel therapeutics to patients around the world. These technologies have presented exciting opportunities for breakthrough medical treatments ...
Designing and implementing auxiliary operational processes
(Massachusetts Institute of Technology, 2008)
Amazon.com, one of the largest and most profitable online retailers, has been experiencing such dramatic growth rates that it must continually update and modify its fulfillment process in order to meet customer demand for ...
Evaluating cost-reduction alternatives and low-cost sourcing opportunities for aerospace castings and forgings
(Massachusetts Institute of Technology, 2008)
As companies continue to outsource large portions of their manufacturing, managing costs in the supply chain is increasingly important in reducing overall costs and remaining competitive. Low-cost sourcing has become an ...
Development of a total landed cost and risk analysis model for global strategic sourcing
(Massachusetts Institute of Technology, 2008)
Total landed cost and supply chain risk analysis are methods that many companies use to assess strategic sourcing decisions. For this project, landed cost is defined as those costs associated with material movement from a ...
Achieving business and operational excellence in the pharmaceutical industry
(Massachusetts Institute of Technology, 2008)
Historically the pharmaceutical industry has been highly profitable. However, the increasing regulatory requirements, bargaining power of buyers, and drug failures together with the threat of biosimilars and decreasing R&D ...
Development of a global facility location analysis tool
(Massachusetts Institute of Technology, 2008)
With an economy and customer base that is global, companies are increasingly expanding outside their home country's borders. Many times this is done to take advantage of lower labor or material rates, to increase proximity ...
Cycle time reduction through wafer starts control
(Massachusetts Institute of Technology, 2008)
Intel's Fab 17, located in Hudson, Massachusetts, has experienced dramatic improvements in its cycle time performance in the last two years. These improvements have been attributed to lean implementation efforts, reduced ...
The enterprise architecting framework applied to the supply organization of a sourcing management center of excellence
(Massachusetts Institute of Technology, 2008)
The basis to develop this thesis was performed after executing an internship in ABB Inc. The main objective of the study was to design the organization to operate the procurement function at a new manufacturing campus.The ...
Enabling manufacturing flexibility issue resolution in advanced vehicle development
(Massachusetts Institute of Technology, 2008)
Manufacturing Flexibility is a broad term used to describe a metric that can be measured in many different ways. Current industry experts agree that Flexibility is one of the key measures that will help the automotive ...