Search
Now showing items 41-48 of 48
An analysis and mitigation of demand variability on external supply chains
(Massachusetts Institute of Technology, 2019)
In the pharmaceutical industry, increasing product complexity, shifts towards specialty medicine and growth in emerging markets have resulted in increased forecast variation and manufacturing complexity for new products. ...
A systematic approach for assessing next generation technologies and solutions in biomanufacturing
(Massachusetts Institute of Technology, 2019)
Amgen is one of the world's leading independent biotechnology companies and competes globally to advance important medicines in a highly competitive marketplace. Biologics manufacturers such as Amgen have traditionally ...
improving contact lens manufacturing through cost modeling and batch production scheduling optimization
(Massachusetts Institute of Technology, 2019)
J&J Vision Care (JJVC) uses production scheduling methods that are not fully optimized, causing over-production of certain SKUs, and reducing capacity for other SKUs on backorder. This makes planning a weekly run-schedule ...
A computational framework for predicting CHO cell culture performance in bioreactors
(Massachusetts Institute of Technology, 2019)
Breaking the trade-off between speed and productivity is a key milestone across industries. In particular, in the biopharmaceutical industry this trade-off is exacerbated by a highly regulated environment, which hinders ...
Quantifying a fair labor value for garment production through prediction of factory efficiency
(Massachusetts Institute of Technology, 2019)
Li&Fung is a world leader in logistics, sourcing, and procurement; connecting manufacturing vendors with major retail brands. Recently, there has been an increasing consumer demand for more sustainably produced and sourced ...
Integrating additive manufacturing into operations at middle market companies
(Massachusetts Institute of Technology, 2019)
Ascent Aerospace's leadership recognizes the transformative potential of additive manufacturing (AM) to the aerospace tooling industry. As a middle market company, Ascent required a deliberate approach to identifying areas ...
Application of risk management frameworks to medical device production development
(Massachusetts Institute of Technology, 2019)
Effective risk management is critical when manufacturing medical products to avoid any potential impact to patients due to supply disruptions or quality excursions. As Flex LTD, an end-to-end manufacturing solutions provider, ...
Data-driven predictive modeling for cell line selection in biopharmaceutical production
(Massachusetts Institute of Technology, 2019)
A critical component of the biopharmaceutical development cycle is the selection of the cell line that will become the Master Cell Bank for product manufacturing for clinical and commercial use. This cell line selection ...