The course employs two 60-minute lectures per week, along with weekly laboratory and recitation sessions.
Lec = Lecture
Lab = Lab
Rec = Recitation
Calendar Table.
| SeS # |
TOPICS |
INSTRUCTORS |
KEY DATES |
| Overview |
| 1 |
Lec 1
Introduction to Course
Introduction to Functional Magnetic Resonance Imaging |
Rick Hoge |
|
| Functional Neural Systems |
| 2 |
Lec 2
Overview of Neural Systems: Neural Systems I
Lab 1
Introduction to Lab, Viewing MR Images, and MatLab®. Safety Video |
Brad Dickerson
Rick Hoge |
|
| 3 |
Lec 3
Overview of Neural Systems: Neural Systems II
Rec 1
Human Subjects and Safety Issues |
Brad Dickerson
Randy Gollub |
|
| 4 |
Lec 4
Overview of Neural Systems: Neural Systems III
Lab 2
MRI Tour |
Brad Dickerson
Rick Hoge |
|
| Imaging Physiology |
| 5 |
Lec 5
Overview of Imaging Physiology
Applied Respiratory and Cardiovascular Physiology I
Rec 2
See Bibliography |
Robert Banzett
Rick Hoge
|
Problem Set 1 due |
| 6 |
Lec 6
Applied Respiratory and Cardiovascular Physiology II
Lab 3
Introduction to fMRI Data Acquisition and Viewing |
Robert Banzett
Rick Hoge |
|
| 7 |
Lec 7
Cerebrovascular Anatomy and Neural Regulation of CNS Blood Flow
Rec 3
Review of Imaging Physiology:
The Big Picture of HST 583 |
Brad Dickerson
Martin Zalesak |
|
| 8 |
Lec 8
Neurovascular Coupling. Global vs. Regionally Specific Changes in CBF and Metabolism
Lab 4
Biophysical Basis of fMRI Signal. Introduction and Lab |
Brad Dickerson
Rick Hoge |
|
| Experiment Design |
| 9 |
Lec 9
General Principles of Experimental Design, point 1
Rec 4 |
Robert Savoy
Nouchine Hadjikhani
|
Problem Set 2 due |
| 10 |
Lec 10
General Principles of Experimental Design, point 2
Psychological State Variables in Imaging
Rec 5 |
Robert Savoy
Anne Blood
|
|
| Physics of Image Acquisition |
| 11 |
Lec 11
Overview of Structural and Functional MRI Signal Acquisition
Lab 5
Biophysical Basis of fMRI Signals, part 2 |
Larry Wald
Rick Hoge |
Problem Set 3 due |
| 12 |
Lec 12
MRI Physics I
Rec 6
Movement Artifacts in fMRI |
Jorge Jovicich
Rick Hoge |
|
| 13 |
Lec 13
MRI Physics II
Lab 6
Improving fMRI Signal using Physiological Data |
Larry Wald
Jennifer Melcher and Irina Sigalovsky |
Lab Report 1 due |
| 14 |
Lec 14
MRI Physics III
Rec 7 |
Larry Wald |
|
| 15 |
Lec 15
MRI Physics IV
Lab 7
Extra Lab Session |
Jorge Jovicich
Rick Hoge and Martin Zalesak |
Lab Report 2 due |
| 16 |
Lec 16
Physics of Diffusion Weighted Imaging
Rec 8 |
David Tuch
Rick Hoge
|
|
| 17 |
Lec 17
Diffusion Weighted Imaging II
Lab 8
Diffusion Gradients Lab |
David Tuch
David Tuch and Rick Hoge |
Lab Report 3 due |
|
Mid-term Exam |
|
|
| Statistical Analysis |
| 18 |
Lec 18
Overview of fMRI Statistical Analysis. Stats I
Lab 9
Statistical Analysis of fMRI Data, part 1 |
Doug Greve
Savoy, Hoge, Greve and Vangel |
Lab Report 4 due |
| 19 |
Lec 19
Overview of fMRI Statistical Analysis. Stats II
Rec 9 |
Doug Greve
Joe Mandeville
|
|
| 20 |
Lec 20
Overview of fMRI Statistical Analysis. Stats III
Lab 10
Statistical Analysis of fMRI Data, part 2 |
Doug Greve
Savoy, Hoge, Greve and Vangel |
|
| 21 |
Lec 21
Overview of fMRI Statistical Analysis. Stats IV
Rec 10 |
Mark Vangel
Steve Stufflebeam
|
|
| 22 |
Lec 22
Overview of fMRI Statistical Analysis. Stats V
Lab 11
Morphometric Analysis |
Mark Vangel
David Kennedy and David Salat |
Problem Set 4 due
Lab Report 5 due |
| 23 |
Lec 23
Overview of fMRI Statistical Analysis. Stats VI
Rec 11 |
Mark Vangel
Chris Moore
|
Lab Report 6 due |
| Structural and Functional Analysis |
| 24 |
Lec 24
Spatial Normalization for Anatomical Analysis. DTI Applications |
David Kennedy |
|
| 25 |
Lec 25
Surface-based Anatomical Analysis |
David Salat |
|
|
Final Exam |
|
|