dc.contributor.author | Sanyal, Sumana | |
dc.contributor.author | Ashour, Joseph | |
dc.coverage.temporal | Spring 2013 | |
dc.date.accessioned | 2023-03-06T16:37:09Z | |
dc.date.available | 2023-03-06T16:37:09Z | |
dc.date.issued | 2013-06 | |
dc.identifier | 7.346-Spring2013 | |
dc.identifier.other | 7.346 | |
dc.identifier.other | IMSCP-MD5-a657ada095e8eecf84a2ae1b66c691b9 | |
dc.identifier.uri | https://hdl.handle.net/1721.1/148314 | |
dc.description.abstract | Co-evolution and adaptation between viruses and humans are often portrayed as a zero-sum biological arms race. Viruses enter host cells equipped with an array of mechanisms to evade the host defense responses and replicate. The rapid rate of mutation of viruses permits evolution of various methodologies for infection, which in turn drive development of non-specific but highly effective host mechanisms to restrict infection. This class will discuss the varied solutions each side has developed as a means for survival. We will use examples drawn from human disease-causing pathogens that contribute seriously to the global health burden, including HIV, influenza and dengue virus. Primary research papers will be discussed to help students learn to pose scientific questions and design and conduct experiments to answer the questions and critically interpret data. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. | en |
dc.language.iso | en-US | |
dc.rights | This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. | en |
dc.rights | Attribution-NonCommercial-ShareAlike 3.0 Unported | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | * |
dc.subject | virus | en |
dc.subject | host | en |
dc.subject | infection | en |
dc.subject | protein-protein interactions | en |
dc.subject | host mimicry | en |
dc.subject | intra-cellular trafficking | en |
dc.subject | host-cell machinery | en |
dc.subject | signaling pathways | en |
dc.subject | antiviral proteins | en |
dc.subject | HIV | en |
dc.subject | influenza | en |
dc.subject | dengue virus | en |
dc.subject | biotechnology | en |
dc.subject | vaccine development | en |
dc.subject | host sensors | en |
dc.subject | IFN production | en |
dc.subject | Secreted IFN | en |
dc.subject | filoviruses | en |
dc.subject | hCMV | en |
dc.subject | IFITM proteins | en |
dc.title | 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 | en |
dc.title.alternative | Virus-host Interactions in Infectious Diseases | en |
dc.audience.educationlevel | Undergraduate | |
dc.subject.cip | 261201 | en |
dc.date.updated | 2023-03-06T16:37:15Z | |