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Biological scaffolds for the peptide-directed assembly of nanoscale materials and devices

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dc.contributor.advisor Angela M. Belcher. en_US Solis, Daniel J., 1978- en_US
dc.contributor.other Massachusetts Institute of Technology. Dept. of Chemistry. en_US 2008-02-28T16:24:40Z 2008-02-28T16:24:40Z 2006 en_US 2006 en_US
dc.identifier.uri en_US
dc.description Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2006. en_US
dc.description Vita. en_US
dc.description Includes bibliographical references. en_US
dc.description.abstract The utilization of biological factors in the design, synthesis and fabrication of nano-scaled materials and devices presents novel, large scale solutions for the realization of future technologies. In particular, we have genetically modified the M13 Filamentous Bacteriophage for its use as a biological scaffold in the peptide-controlled nucleation and patterning of nanoscale semiconducting and magnetic materials. Through evolutionary phage display screening of inorganic substrates, functional peptides that influence material properties such as size, phase and composition during nucleation have been identified. The incorporation of these specific, nucleating peptides into the generic scaffold of the M13 coat structure provides a viable linear template for the directed synthesis of semiconducting and magnetic nanowires. Through further modification of the remaining proteins on the virus scaffold, other functionalities can be incorporated such as the directed patterning of the virus/nanowires assemblies into nanoscaled devices with tunable properties as determined by the genetic information carried within the virus scaffold. Multi-functional viruses provide a truly self assembled system for the design and execution of a myriad of nanoscaled devices in a green, scalable and cost effective manner. en_US
dc.description.statementofresponsibility by Daniel Joseph Solis. en_US
dc.format.extent 108 leaves en_US
dc.language.iso eng en_US
dc.publisher Massachusetts Institute of Technology en_US
dc.rights M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. en_US
dc.rights.uri en_US
dc.subject Chemistry. en_US
dc.title Biological scaffolds for the peptide-directed assembly of nanoscale materials and devices en_US
dc.type Thesis en_US Ph.D. en_US
dc.contributor.department Massachusetts Institute of Technology. Dept. of Chemistry. en_US
dc.identifier.oclc 70851508 en_US

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