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Design of Specific Mammalian Promoters by in silico Prediction

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Title: Design of Specific Mammalian Promoters by in silico Prediction
Author: Heinemann, Tim; Kramer, Stephen; Velten, Lars; Kranz, Anna-Lena; Bauer, Tobias; Faura, Marti Bernardo; Konig, Rainer; Keienburg, Jens; Eils, Roland; Iwamoto, Nao
Issue Date: 2009-10-30
Abstract: The purpose of this RFC is to provide a) a method for the design of rational synthetic promoter sequences based on a statistical analysis about the spatial preference of transcription factor binding sites in human promoter sequences and b) further introduce standards to provide compatibility with data formats introduced in this RFC. Description of promoters generated by this method can be found at http://2009.igem.org/Team:Heidelberg/HEARTBEAT_database.
URI: http://hdl.handle.net/1721.1/49520
Series/Report no.: BBF RFC;43
Keywords: modeling

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