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BioJADE: A Design and Simulation Tool for Synthetic Biological Systems

Research and Teaching Output of the MIT Community

Show simple item record Goler, Jonathan A. en_US 2004-10-20T20:32:27Z 2004-10-20T20:32:27Z 2004-05-28 en_US
dc.identifier.other AITR-2004-003 en_US
dc.description.abstract The next generations of both biological engineering and computer engineering demand that control be exerted at the molecular level. Creating, characterizing and controlling synthetic biological systems may provide us with the ability to build cells that are capable of a plethora of activities, from computation to synthesizing nanostructures. To develop these systems, we must have a set of tools not only for synthesizing systems, but also designing and simulating them. The BioJADE project provides a comprehensive, extensible design and simulation platform for synthetic biology. BioJADE is a graphical design tool built in Java, utilizing a database back end, and supports a range of simulations using an XML communication protocol. BioJADE currently supports a library of over 100 parts with which it can compile designs into actual DNA, and then generate synthesis instructions to build the physical parts. The BioJADE project contributes several tools to Synthetic Biology. BioJADE in itself is a powerful tool for synthetic biology designers. Additionally, we developed and now make use of a centralized BioBricks repository, which enables the sharing of BioBrick components between researchers, and vastly reduces the barriers to entry for aspiring Synthetic Biologists. en_US
dc.format.extent 54 p. en_US
dc.format.extent 5905018 bytes
dc.format.extent 1459615 bytes
dc.format.mimetype application/postscript
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.relation.ispartofseries AITR-2004-003 en_US
dc.subject AI en_US
dc.subject BioJADE en_US
dc.subject Synthetic Biology en_US
dc.subject DNA en_US
dc.title BioJADE: A Design and Simulation Tool for Synthetic Biological Systems en_US

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