Browsing Doctoral Theses by Title
Now showing items 13637-13656 of 22282
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The N-end rule degradation pathway : substrate recognition and staged delivery to the CIpAP protease by the CIpS adaptor protein
(Massachusetts Institute of Technology, 2011)Regulated protein degradation is crucial in the regulation of many physiological processes as well as in protein quality control. In all organisms, ranging from bacteria to mammals, ATP-dependent proteases carry out regulated ... -
(N-heterocyclic-carbene)Copper(I)-catalyzed carbon-carbon bond formation using carbon dioxide
(Massachusetts Institute of Technology, 2007)This thesis presents work towards the development of a new catalytic C-C bond forming reaction. Alkynes and olefins insert into [(IPr)CuH]2 (IPr = N,N-bis-(2,6-diisopropylphenyl)-1,3-imidazol-2-ylidene) to give copper vinyl ... -
N.M.R. chemical shift imaging
(Massachusetts Institute of Technology, 1984) -
Naming and synchronization in a decentralized computer system.
(Massachusetts Institute of Technology, 1979) -
Nano Vacuum Channel Devices for Electronics and Ultrafast Nanophotonics
(Massachusetts Institute of Technology, 2022-05)Recent years have seen a surge of interest in nano vacuum channel (NVC) devices due to their low power requirements, radiation hardness, integrability, and ultrafast switching times. Planar NVC devices are ideal candidates ... -
Nano-cellular microstructure evolution in ion-induced chemical vapor deposition (II-CVD) of copper
(Massachusetts Institute of Technology, 2003)A systematic investigation of the microstructure produced in ion-induced chemical vapor deposition (11-CVD) of copper from copper(I)hexafluoroacetylacetonatevinyltrimethylsilane (Cu(I)hfacVTMS) gas precursor is reported. ... -
Nano-scale Glucose Fuel Cells for Energy Harvesting in the Human Body Based on Proton Conduction in Cerium Oxide
(Massachusetts Institute of Technology, 2021-06)Future implantable medical devices such as sensors, drug delivery systems, and electroceuticals require efficient, reliable, and highly miniaturized power sources. To date, the predominant power source of implants is the ... -
A nano-stepping robotic instrumentation platform
(Massachusetts Institute of Technology, 2013)The development of an Autonomous Nano-stepping Tool (ANT) system is presented. Each ANT is a small, tripodal, robotic instrument capable of untethered precision motion within a quasi-three-dimensional workspace of arbitrary ... -
A nanobody suite for yeast scaffold nucleoporins provides details of the Y complex structure and nuclear pore complex assembly
(Massachusetts Institute of Technology, 2020)Nuclear pore complexes (NPCs) are the main conduits for molecular exchange across the nuclear envelope. The NPC is a modular assembly of ~500 individual proteins, called nucleoporins or nups, that can be classified into ... -
Nanocomposite catalysts for soot combustion and propane steam reforming
(Massachusetts Institute of Technology, 2007)A nanocomposite system, CuO-Ag/CeO 2, has been successfully developed to complete carbon black combustion by 400*C. This novel catalyst has excellent potential for application in the emission control of soot particulates ... -
Nanocomposites as thermoelectric materials
(Massachusetts Institute of Technology, 2010)Thermoelectric materials have attractive applications in electric power generation and solid-state cooling. The performance of a thermoelectric device depends on the dimensionless figure of merit (ZT) of the material, ... -
Nanocomposites for nitrogen oxide emissions control in lean-burn engines
(Massachusetts Institute of Technology, 2004)(cont.) reducing agent than propane in the SCR of NO. Pt-Rh/CuO/A1₂O₃ nanocomposites capable of adsorbing SO₂ in oxygen-rich environment as metal sulfates and releasing SO₂ in reducing atmosphere were synthesized with ... -
Nanocontacts controlled atom-by-atom in an ion-crystal friction emulator
(Massachusetts Institute of Technology, 2016)Friction is the basic, ubiquitous mechanical interaction between two surfaces that results in resistance to motion and energy dissipation. To test long-standing atomistic models of friction processes at the nanoscale, we ... -
Nanocrystal-molecule energy transfer conjugates for chemical and biological sensing
(Massachusetts Institute of Technology, 2008)New tools and probes are constantly being developed for chemical and biological sensing. As novel materials emerge, growing demand for sensing in specific applications can be addressed. One such class of materials is ... -
Nanocrystal/J-aggregate constructs : chemistry, energy transfer, and applications
(Massachusetts Institute of Technology, 2011)The interaction of light with matter is one of the most central subjects to modern chemistry. Two types of materials, semiconductor nanocrystals and J-aggregates of cyanine dyes, have been developed chiefly due to their ... -
Nanocrystalline alloys : enhanced strengthening mechanisms and mechanically-driven structural evolution
(Massachusetts Institute of Technology, 2011)Nanocrystalline materials have experienced a great deal of attention in recent years, largely due to their impressive array of physical properties. In particular, nanocrystalline mechanical behavior has been of interest, ... -
Nanocrystalline perovskites for catalytic combustion and oxygen separation
(Massachusetts Institute of Technology, 2002)Nanocrystalline perovskites (Lal-xAMnl-yByO3) were successfully synthesized with higher surface area and smaller grain size by chemical co-precipitation compared to solid-state and complexation/combustion synthesis routes. ... -
Nanocrystallization confined to porous matrices with and without surface functionalization effects
(Massachusetts Institute of Technology, 2018)Poorly water-soluble active pharmaceutical ingredients (APIs), which represent a major fraction of the molecules in drug discovery and development, are a challenge to the pharmaceutical industry given their low bioavailability. ... -
Nanoemulsion-Loaded Hydrogels For Advanced Pharmaceutical Formulations
(Massachusetts Institute of Technology, 2022-09)Pharmaceutical formulation plays an important role in transforming a drug substance into the final drug product taken by a patient. It involves processes that combine an active pharmaceutical ingredient (API) and a mixture ... -
Nanoengineered hierarchical advanced composites with nanofiber interlaminar reinforcement for enhanced laminate-level mechanical performance
(Massachusetts Institute of Technology, 2020)At present, there is a need for novel, scalable, and high-performance structural materials that offer unprecedented combinations of stiffness, strength, and toughness at a low density, which can serve in a variety of ...