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The comprehension of main and embedded clauses
(Massachusetts Institute of Technology, 1998)
Chronic stress-dependent activation of somatostatin neurons in the nucleus accumbens facilitates maladaptive eating behaviors
(Massachusetts Institute of Technology, 2016)
Stressors are known to impact eating behaviors. However, recapitulating the intricate interplay between chronic stress and aberrant human eating patterns in an animal model remains a challenge. Notably, binge eating, a ...
Synaptic plasticity in the MyosinVa mutant mouse
(Massachusetts Institute of Technology, 2009)
The trafficking of essential proteins into spines is an important aspect of synaptic plasticity. MyosinVa, an actin-based motor protein, has been implicated in the synaptic delivery of AMPARs during LTP [1]. However an ...
Microfluidics for Calcium Imaging of C.elegans Neurons During Temporally Precise Odor Stimulation
(Massachusetts Institute of Technology, 2021-09)
How neurons process sensory stimuli to give rise to different behaviors is one of the most pursued and complex questions in neuroscience. With recent technologies, scientists have been able to map how sensory cues, like ...
Seeking the neural basis of grammar : English noun and verb morphological processing investigated with rapid event-related fMRI and intracortical electrophysiology
(Massachusetts Institute of Technology, 2003)
(cont.) the functionality of the fMRI data analysis and visualization tools used at Massachusetts General Hospital. I analyze and interpret an 18-subject fMRI experiment I ran using the new task design and software tools. ...
Knockout of the glutamate transporter GLT-1 specifically from neurons drastically alters transcriptome profiles in CA3, CA1, and Striatum
(Massachusetts Institute of Technology, 2015)
Precise regulation of glutamate homeostasis is critical for normal brain function, as its disruption can impair excitatory transmission and result in neurodegenerative and neuropsychiatric disorders. Critical to maintaining ...
Judicious imitation : children differentially imitate deterministically and probabilistically effective actions
(Massachusetts Institute of Technology, 2007)
Three studies look at whether the assumption of causal determinism (the assumption that all else being equal, causes generate effects deterministically) affects children's imitation of modeled actions. We show that, even ...
Investigating the influence of LH-projecting BLA neurons upon motivated behavioral responding and appetitive learning
(Massachusetts Institute of Technology, 2015)
To optimize survival, organisms must be able to learn contingencies between external stimuli and rewards and appropriately respond to these associations. Deficits in reward-related learning or reward-seeking are thought ...
Generation and tuning of learned sensorimotor behavior by multiple neural circuit architectures
(Massachusetts Institute of Technology, 2015)
Organisms have a remarkable ability to respond to complex sensory inputs with intricate, tuned motor patterns. How does the brain organize and tune these motor responses, and are certain circuit architectures, or connectivity ...
Anthropomorphic bias in naming
(Massachusetts Institute of Technology, 1999)