Search
Now showing items 1-10 of 28
Improving predictability of cell culture processes during biologics manufacturing scale-up through hybrid modeling
(Massachusetts Institute of Technology, 2020)
In the biotechnology industry, commercial manufacturing of biologic drugs occurs in large-scale production bioreactors (15,000L), but process development occurs in lab-scale production bioreactors (2-3L). Cell culture ...
Predicting and Preventing Unsafe Events at an Enterprise
(Massachusetts Institute of Technology, 2023-06)
Amgen Incorporated, like many organizations with manufacturing operations, has undesirable incidents. Corporate workers trip and fall. Contractors get cuts that require first aid. Shop floor operators can be injured by ...
Inference of the Novel Coronavirus 2019 in Patients fitted with Boston Scientific Medical Hardware
(Massachusetts Institute of Technology, 2023-06)
As Boston Scientific’s Rhythm Management business is challenged by an increasingly commoditized market it is important to find new opportunities to diversify the products and services that the company offers. Traditionally, ...
Transmission system overvoltage mitigation through the use of distributed generation (DG) smart inverters
(Massachusetts Institute of Technology, 2020)
The objective of this project is to demonstrate the technical ability and cost-effectiveness of reducing electric transmission system overvoltage violations using distributed generation (DG) smart inverters connected to ...
Streamlining Financial Analysis for Novel Robotics Concepts
(Massachusetts Institute of Technology, 2022-05)
Over the past decade e-commerce shipment volumes have risen dramatically, and online retailers,lead by Amazon, have invested significantly in robotics technologies to meet capacity needs. Before making these investments, ...
Enabling Proactive Quality in Commercial Airplanes using Natural Language Processing
(Massachusetts Institute of Technology, 2022-05)
Quality management systems traditionally draw insight from structured, often numerical, sources of data; unstructured, free-text representations of quality data are less frequently employed despite having high informational ...
End-to-End Artificial Intelligence Lifecycle Management
(Massachusetts Institute of Technology, 2022-05)
In this digital era, companies are battling at the forefront of innovation to share the next transformative idea with the world. Many of these ideas apply Artificial Intelligence (AI) to solve important societal problems. ...
Fulfillment Simulation and Inventory Location Optimization
(Massachusetts Institute of Technology, 2022-05)
For a large, global retailer, the expansion towards digital business has motivated a shift in supply chain strategy. The retailer is in the process of transitioning from traditionally using national hubs for fulfillment ...
Deep Learning Image Augmentation using Inpainting with Partial Convolution and GANs
(Massachusetts Institute of Technology, 2021-06)
The 21st century has seen the remarkable transformation of machine vision by deep learning. This has enabled intelligent systems like autonomous vehicles and facial recognition software. However, the success of deep learning ...
The Limits of Analytics During Black Swan Events A Case Study of the Covid-19 Global Pandemic
(Massachusetts Institute of Technology, 2021-06)
During statistically unlikely events (Black Swan events) analytical models fail to provide their expected level of fidelity: their error can increase by several hundred percent. The modern economy is built on such analytical ...