7.341 The DNA Damage Response as a Target for Anti-Cancer Therapy, Fall 2008

Author(s)
Reinhardt, Hans Christian
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Alternative title
The DNA Damage Response as a Target for Anti-Cancer Therapy
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Abstract
Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand of cell cycle regulation and DNA damage checkpoints that act as powerful emergency brakes to prevent cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Date issued
2008-12
URI
https://hdl.handle.net/1721.1/148358
Department
Massachusetts Institute of Technology. Department of Biology
Other identifiers
7.341-Fall2008
Other identifiers
7.341
IMSCP-MD5-81ab5efd1184a04f9b9fca12b2b7e700
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Keywords
DNA, damage checkpoints, cancer, cells, human cells, exogenous, endogenous, checkpoints, gene, signaling, cancer biology, cancer prevention, primary sources, discussion, DNA damage, molecular, enzyme, cell cycle, extracellular cues, growth factors, Cdk regulation, cyclin-dependent kinase, p53, tumor suppressor, apoptosis, signaling, MDC1, H2AX, Rad50, Fluorescence activated cell sorter, Chk1, mutant
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