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Synthetic Biology

Research and Teaching Output of the MIT Community

Synthetic Biology

 

Synthetic biology refers to both (a) the design and fabrication of biological components and systems that do not already exist in the natural world and (b) the re-design and fabrication of existing biological systems.

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  • BBF RFC 112: Synthetic Biology Open Language (SBOL) Version 2.1.0 
    Beal, Jacob; Cox, Robert Sidney; Grünberg, Raik; McLaughlin, James; Nguyen, Tramy; Macklin, Chris; Bissell, Michael; Madsen, Curtis; Roehner, Nicholas; Oberortner, Ernst; Misirli, Goksel; Clancy, Kevin; Pocock, Matthew; Zhang, Zhen; Myers, Chris; Zhang, Michael; Samineni, Meher; Zundel, Zach; Bartley, Bryan; Choi, Kiri; Gennari, John H.; Sauro, Herbert (2016-11-10)
    The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information.
  • Should We Synthesize A Human Genome? 
    Endy, Drew; Zoloth, Laurie (2016-05-10)
    Given that human genome synthesis is a technology that could be used to completely redefine the core of what now joins all of humanity together as a species, we argue that discussions of making such capacities real, like ...
  • Cellular Computing, ISAT Summer Study, August 1996 
    Knight, Thomas; Matsudaira, Paul (2016-01-27)
    Create and exploit a novel technology for information processing and manufacturing by controlling processes in living cells.
  • BBF RFC 108: Synthetic Biology Open Language (SBOL) Version 2.0.0 
    Bartley, Bryan; Beal, Jacob; Clancy, Kevin; Misirli, Goksel; Roehner, Nicholas; Sauro, Herbert; Oberortner, Ernst; Madsen, Curtis; Pocock, Matthew; Wipat, Anil; Nguyen, Tramy; Zhang, Zhen; Myers, Chris; Gennari, John H.; Bissell, Michael (2015-09-07)
    The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing ...
  • BBF RFC 94: Type IIS Assembly for Bacterial Transcriptional Units: A Standardized Assembly Method for Building Bacterial Transcriptional Units Using the Type IIS Restriction Enzymes BsaI and BbsI 
    Haddock, Traci L.; Densmore, Douglas M.; Appleton, Evan; Carr, Swati; Iverson, Sonya; De Freitas, Monique; Jin, Shawn; Awtry, Jake; Desai, Devina; Lozanoski, Thomas; Shah, Pooja; Agarwal, Yash; Lewis, Kathleen; Pacheco, Alan (2015-08-28)
    This RFC94 describes an assembly standard based on the Type IIS restriction enzymes BsaI and BbsI (also called BpiI). This assembly standard is based upon the Modular Cloning (MoClo) assembly strategy, which was introduced ...
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