Browsing MIT Open Access Articles by Author "Nabel, Christopher S"

Now showing items 1-2 of 2

    • Nucleotide imbalance decouples cell growth from cell proliferation 

      Diehl, Frances F; Miettinen, Teemu P; Elbashir, Ryan; Nabel, Christopher S; Darnell, Alicia M; e.a. (Springer Science and Business Media LLC, 2022)
      <jats:title>Abstract</jats:title><jats:p>Nucleotide metabolism supports RNA synthesis and DNA replication to enable cell growth and division. Nucleotide depletion can inhibit cell growth and proliferation, but how cells ...

    • Patient-Derived Xenografts to Study Cancer Metabolism: When Does X Mark the Spot? 

      Nabel, Christopher S; Vander Heiden, Matthew G (American Association for Cancer Research (AACR), 2021)
      <jats:title>Abstract</jats:title> <jats:p>A major goal of cancer research is to understand the requirements for cancer growth and progression that can be exploited to treat patients. Model systems reduce ...