Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
Author(s)
Hook, Andrew L.; Chang, Chien-Yi; Scurr, David J.; Williams, Paul; Davies, Martyn C.; Alexander, Morgan R.; Anderson, Daniel Griffith; Langer, Robert S; ... Show more Show less
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The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone; rather, the surface composition of the polymer plays the key role.
Date issued
2014-02Department
Harvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Department of Chemical Engineering; Koch Institute for Integrative Cancer Research at MITJournal
Advanced Healthcare Materials
Publisher
Wiley Blackwell
Citation
Hook, Andrew L., Chien-Yi Chang, David J. Scurr, Robert Langer, Daniel G. Anderson, Paul Williams, Martyn C. Davies, and Morgan R. Alexander. “ Thermally Switchable Polymers Achieve Controlled Escherichia Coli Detachment .” Adv. Healthcare Mater. 3, no. 7 (February 4, 2014): 1020–1025.
Version: Author's final manuscript
ISSN
21922640