Show simple item record

Tunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cells

dc.contributor.authorAceto, Nicola
dc.contributor.authorLim, Eugene J.
dc.contributor.authorSullivan, James P.
dc.contributor.authorJensen, Anne E.
dc.contributor.authorZeinali, Mahnaz
dc.contributor.authorMartel, Joseph M.
dc.contributor.authorAranyosi, Alexander J.
dc.contributor.authorLi, Wei
dc.contributor.authorCastleberry, Steven
dc.contributor.authorBardia, Aditya
dc.contributor.authorSequist, Lecia V.
dc.contributor.authorHaber, Daniel A.
dc.contributor.authorMaheswaran, Shyamala
dc.contributor.authorHammond, Paula T.
dc.contributor.authorToner, Mehmet
dc.contributor.authorStott, Shannon L.
dc.contributor.authorReategui, Eduardo
dc.date.accessioned2016-03-24T15:05:39Z
dc.date.available2016-03-24T15:05:39Z
dc.date.issued2015-01
dc.date.submitted2014-12
dc.identifier.issn09359648
dc.identifier.issn1521-4095
dc.identifier.urihttp://hdl.handle.net/1721.1/101769
dc.description.abstractA layer-by-layer gelatin nanocoating is presented for use as a tunable, dual response biomaterial for the capture and release of circulating tumor cells (CTCs) from cancer patient blood. The entire nanocoating can be dissolved from the surface of microfluidic devices through biologically compatible temperature shifts. Alternatively, individual CTCs can be released through locally applied mechanical stress.en_US
dc.language.isoen_US
dc.publisherWiley Blackwellen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/adma.201404677en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleTunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cellsen_US
dc.typeArticleen_US
dc.identifier.citationReategui, Eduardo, Nicola Aceto, Eugene J. Lim, James P. Sullivan, Anne E. Jensen, Mahnaz Zeinali, Joseph M. Martel, et al. “Tunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cells.” Advanced Materials 27, no. 9 (January 15, 2015): 1593–1599.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Scienceen_US
dc.contributor.mitauthorLim, Eugene J.en_US
dc.contributor.mitauthorLi, Weien_US
dc.contributor.mitauthorCastleberry, Stevenen_US
dc.contributor.mitauthorHammond, Paula T.en_US
dc.relation.journalAdvanced Materialsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsReategui, Eduardo; Aceto, Nicola; Lim, Eugene J.; Sullivan, James P.; Jensen, Anne E.; Zeinali, Mahnaz; Martel, Joseph M.; Aranyosi, Alexander J.; Li, Wei; Castleberry, Steven; Bardia, Aditya; Sequist, Lecia V.; Haber, Daniel A.; Maheswaran, Shyamala; Hammond, Paula T.; Toner, Mehmet; Stott, Shannon L.en_US
dc.identifier.orcidhttps://orcid.org/0000-0001-6070-7356
mit.licenseOPEN_ACCESS_POLICYen_US


Files in this item

Thumbnail
Name:
Tunable nanostructured.pdf
Size:
538.1Kb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record