Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial

Author(s)
Liu, Harris; Kim, Yoojeong; Mello, Kerrianne; Lovaasen, John; Shah, Apoorva; ... Show more
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Abstract
The currently used multistep chemical synthesis for making surfaces antimicrobial by attaching to them hydrophobic polycations is replaced herein by an aerosol-assisted plasma deposition procedure. To this end, N,N-hexyl,methyl-PEI (HMPEI) is directly plasma-coated onto a glass surface. The resultant immobilized HMPEI coating has been thoroughly characterized and shown to be robust, bactericidal against Escherichia coli, and virucidal against human influenza virus.
Date issued
2013-10
URI
http://hdl.handle.net/1721.1/107156
Department
Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Chemistry
Journal
Applied Biochemistry and Biotechnology
Publisher
Springer US
Citation
Liu, Harris et al. “Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial.” Applied Biochemistry and Biotechnology 172.3 (2014): 1254–1264.
Version: Author's final manuscript
ISSN
0273-2289
1559-0291
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