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dc.contributor.authorCeliz, Adam D.
dc.contributor.authorDavies, Martyn C.
dc.contributor.authorDenning, Chris
dc.contributor.authorAlexander, Morgan R.
dc.contributor.authorTibbitt, Mark W
dc.contributor.authorLanger, Robert S
dc.contributor.authorAnderson, Daniel Griffith
dc.contributor.authorPatel, Asha
dc.date.accessioned2017-03-06T16:05:06Z
dc.date.available2017-03-06T16:05:06Z
dc.date.issued2016-01
dc.date.submitted2015-12
dc.identifier.issn1359-0286
dc.identifier.urihttp://hdl.handle.net/1721.1/107190
dc.description.abstractInsights into the complex stem cell niche have identified the cell–material interface to be a potent regulator of stem cell fate via material properties such as chemistry, topography and stiffness. In light of this, materials scientists have the opportunity to develop bioactive materials for stem cell culture that elicit specific cellular responses. To accelerate materials discovery, high throughput screening platforms have been designed which can rapidly evaluate combinatorial material libraries in two and three-dimensional environments. In this review, we present screening platforms for the discovery of material properties that influence stem cell behavior.en_US
dc.description.sponsorshipEngineering and Physical Sciences Research Councilen_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Ruth L. Kirschstein National Research Service Award F32HL122009)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant R01 DE016516)en_US
dc.language.isoen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.cossms.2016.02.002en_US
dc.rightsCreative Commons Attribution 4.0 International Licenseen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceElsevieren_US
dc.titleHigh throughput screening for discovery of materials that control stem cell fateen_US
dc.typeArticleen_US
dc.identifier.citationPatel, Asha K. et al. “High Throughput Screening for Discovery of Materials That Control Stem Cell Fate.” Current Opinion in Solid State and Materials Science 20.4 (2016): 202–211.en_US
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.departmentKoch Institute for Integrative Cancer Research at MITen_US
dc.contributor.mitauthorPatel, Asha K
dc.contributor.mitauthorTibbitt, Mark W
dc.contributor.mitauthorLanger, Robert S
dc.contributor.mitauthorAnderson, Daniel Griffith
dc.relation.journalCurrent Opinion in Solid State and Materials Scienceen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsPatel, Asha K.; Tibbitt, Mark W.; Celiz, Adam D.; Davies, Martyn C.; Langer, Robert; Denning, Chris; Alexander, Morgan R.; Anderson, Daniel G.en_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-7266-9251
dc.identifier.orcidhttps://orcid.org/0000-0002-4917-7187
dc.identifier.orcidhttps://orcid.org/0000-0003-4255-0492
dc.identifier.orcidhttps://orcid.org/0000-0001-5629-4798
mit.licensePUBLISHER_CCen_US


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