| dc.contributor.author | Keating, John H. | |
| dc.contributor.author | Nakamura, Kenta | |
| dc.contributor.author | Edelman, Elazer R | |
| dc.date.accessioned | 2018-08-14T18:19:02Z | |
| dc.date.available | 2018-08-14T18:19:02Z | |
| dc.date.issued | 2016-05 | |
| dc.identifier.issn | 2211-7458 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/117362 | |
| dc.description.abstract | Contemporary endovascular stents are the product of an iterative design and development process that leverages evolving concepts in vascular biology and engineering. This article reviews how insights into vascular pathophysiology, materials science, and design mechanics drive stent design and explain modes of stent failure. Current knowledge of pathologic processes is providing a more complete picture of the factors mediating stent failure. Further evolution of endovascular stents includes bioresorbable platforms tailored to treat plaques acutely and to then disappear after lesion pacification. Ongoing refinement of stent technology will continue to require insights from pathology to understand adverse events, refine clinical protocols, and drive innovation. Keywords: Coronary artery disease; Pathology; Bare metal stent; Drug-eluting stent; In-stent restenosis; In-stent thrombosis; Atherosclerosis; Neoatherosclerosis | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Grant R01 GM-49039) | en_US |
| dc.publisher | Elsevier BV | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1016/J.ICCL.2016.02.006 | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
| dc.source | Prof. Edelman | en_US |
| dc.title | Pathology of Endovascular Stents | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Nakamura, Kenta et al. “Pathology of Endovascular Stents.” Interventional Cardiology Clinics 5, 3 (July 2016): 391–403 © 2016 Elsevier Inc | en_US |
| dc.contributor.department | Institute for Medical Engineering and Science | en_US |
| dc.contributor.mitauthor | Nakamura, Kenta | |
| dc.contributor.mitauthor | Edelman, Elazer R | |
| dc.relation.journal | Interventional Cardiology Clinics | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2018-08-13T18:49:02Z | |
| dspace.orderedauthors | Nakamura, Kenta; Keating, John H.; Edelman, Elazer Reuven | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0002-9209-597X | |
| dc.identifier.orcid | https://orcid.org/0000-0002-7832-7156 | |
| mit.license | PUBLISHER_CC | en_US |
