Doctoral Theses: Recent submissions
Now showing items 10-12 of 23230
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Biologically Interpretable Representation Learning for Mechanistic Insights into Cancer Immunotherapy Resistance
(Massachusetts Institute of Technology, 2025-09)Resistance to immune checkpoint inhibitors (ICIs) remains a critical barrier to effective cancer therapy, driven by complex, multi-scale interactions that current biomarkers often fail to capture. This dissertation introduces ... -
Geometric interpretations of structural demand for the analysis and reduction of design complexity
(Massachusetts Institute of Technology, 2025-09)This dissertation presents a computational framework to effectively interpret the distribution of structural demand that emerges from the design of large-scale structural systems, and develops methods for its quantification ... -
The Inhabited Arctic: Architecture, Time, and the Making of the Past in the Bering Strait (1760–1980)
(Massachusetts Institute of Technology, 2025-09)Our view of antiquity is not objective. From the eighteenth century on, the same actors and institutions involved in colonizing the Arctic shaped understandings of its deep past. Commercial whalers erected outposts on the ...
